Cyclosporin A D4
| Product Name | Cyclosporin A D4 |
|---|---|
| Alternate Names | Cyclosporin Stable Isotopes, Stable Isotopes of Cyclosporin |
| CAT No. | CS-O-11129 |
| CAS No. | 59865-13-3 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 1206.64 g/mol |
| Mol. For. | C₆₂H₁₀₇D₄N₁₁O₁₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Cyclosporin |
| Purity | Not less than 95 % |
| Smileys | O[C@@H]([C@](C(N[C@H](C(N(CC(N([C@H](C(N[C@@](C(N([C@H]1CC(C)C)C)=O)([H])C(C)C)=O)CC(C)C)C)=O)C)=O)CC)=O)([H])N(C([C@](N(C([C@@H](N(C([C@](N(C([C@H](NC([C@@H](NC1=O)C)=O)C)=O)C)([H])CC(C)C)=O)C)CC(C)C)=O)C)([H])C(C)C)=O)C)[C@H](C)C/C=C([2H])/C([2H])([2H])匀䰀开匀 |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Cyclosporin A D4, also known as CsA D4, is a deuterated form of Cyclosporin A, a cyclic undecapeptide that is widely used as an immunosuppressant drug. CsA D4 is specifically used in pharmacokinetic studies to determine the metabolic stability and bioavailability of Cyclosporin A in the body. It is a labeled drug that contains four deuterium atoms, which replace four hydrogen atoms in the molecular structure of Cyclosporin A. This labeling makes CsA D4 a useful tool for mass spectrometry-based analysis, as it enables accurate quantification of Cyclosporin A levels in biological samples.
Cyclosporin A D4 has a molecular formula of C62H111D4N11O12 and a molecular weight of 1202.87 g/mol. It is a hydrophobic molecule that is poorly soluble in water, but readily dissolves in organic solvents such as ethanol, methanol, and chloroform. The drug is administered orally or intravenously, and its absorption is influenced by factors such as food intake, liver function, and drug interactions.
Cyclosporin A D4 works by inhibiting the activity of T-lymphocytes, a type of white blood cell that plays a crucial role in the immune system's response to foreign substances. By blocking T-cell activation, CsA D4 prevents the body from rejecting transplanted organs, and it is used in the treatment of autoimmune diseases such as rheumatoid arthritis and psoriasis. However, the drug has several side effects, including nephrotoxicity, hypertension, and increased susceptibility to infections.
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Related Compounds
Cyclosporin A D13 | Cyclosporin A-D4 Acetate | Cyclosporin AM 1-d3 | Cyclosporin AM 9-d6 | Dehydro Cyclosporin A-D4 | Cyclosporin A-D4 Acetate |