Dolutegravir D3
| Product Name | Dolutegravir D3 |
|---|---|
| Alternate Names | Dolutegravir Stable Isotopes, Stable Isotopes of Dolutegravir |
| CAT No. | CS-O-03645 |
| CAS No. | 1051375-16-6 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | IN-Stock |
| Mol. Wt. | 422.40 g/mol |
| Mol. For. | C20H16D3F2N3O5 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Dolutegravir |
| Purity | Not less than 90 % |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | O=C(N([C@@H]1C)[C@](OCC1)([H])CN2C=C(C(NC([2H])([2H])C(C=CC(F)=C3[2H])=C3F)=O)C4=O)C2=C4O |
| Canonical Smiles | CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O |
| InchIKey | RHWKPHLQXYSBKR-BMIGLBTASA-N |
| Inchl | InChI=1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 |
| IUPAC | (3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Dolutegravir D3 is a medication that belongs to the class of drugs known as integrase strand transfer inhibitors (INSTIs). It is used in combination with other medications to treat human immunodeficiency virus (HIV) infection. Dolutegravir D3 works by blocking the integrase enzyme, which is necessary for HIV to multiply and infect other cells. This medication helps to reduce the amount of HIV in the body and increase the number of CD4 cells, which are important for maintaining a healthy immune system.
Chemically, Dolutegravir D3 is a deuterated version of dolutegravir, which means that some of the hydrogen atoms in the molecule have been replaced with deuterium atoms. This modification does not change the way the drug works, but it can improve its pharmacokinetic properties, such as its absorption, distribution, metabolism, and excretion. Dolutegravir D3 is also considered a prodrug, which means that it is converted into an active form in the body.
Dolutegravir D3 is typically taken once a day, with or without food. It is usually prescribed as part of a regimen that includes at least two other antiretroviral medications. Common side effects of Dolutegravir D3 include headache, nausea, diarrhea, and insomnia. Rare but serious side effects may include allergic reactions, liver problems, and changes in mood or behavior.
In conclusion, Dolutegravir D3 is a highly effective medication for the treatment of HIV infection. Its unique chemical properties make it a valuable addition to the arsenal of antiretroviral drugs available today. As always, it is important to consult with a healthcare provider before starting any new medication.
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Related Compounds
Dolutegravir D6 | Dolutegravir-d4 | Dolutegravir-d5 |