Ibuprofen Sorbitol Ester (Mixture of Diastereomers)

Ibuprofen Sorbitol Ester (ISE) is a mixture of diastereomers that is commonly used as a nonsteroidal anti-inflammatory drug (NSAID) to reduce pain, fever, and inflammation. It is a derivative of ibuprofen, which is a widely used over-the-counter medication for pain relief. The chemical structure of ISE consists of an ibuprofen molecule attached to a sorbitol molecule, which enhances its solubility and absorption in the body. ISE works by inhibiting the production of prostaglandins, which are responsible for causing pain and inflammation. It is commonly used to treat conditions such as headaches, toothaches, menstrual cramps, arthritis, and other types of pain. The chemical properties of ISE include a molecular weight of 352.4 g/mol, a melting point of 84-86°C, and a solubility of 1 g/8 mL in water. It is considered a relatively safe medication when taken as directed, although it can cause side effects such as stomach upset, dizziness, and allergic reactions in some individuals. In conclusion, ISE is a widely used medication for pain relief and inflammation reduction. Its chemical properties and mechanism of action make it an effective NSAID for treating a variety of conditions. However, it is important to use ISE as directed and to be aware of potential side effects.