Nilotinib Genotoxic Impurity 1

Product Name Nilotinib Genotoxic Impurity 1
Alternate Names Nilotinib Impurities, Impurities of Nilotinib
CAT No. CS-O-12088
CAS No. 641571-11-1
Category Impurities
Stock IN-Stock
Mol. Wt. 241.21 g/mol
Mol. For. C₁₁H₁₀F₃N₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nilotinib
Purity 95%
Therapeutic Anti-Cancer / Oncology
Smileys FC(F)(C1=CC(N)=CC(N2C=C(C)N=C2)=C1)F
Canonical Smiles CC1=CN(C=N1)C2=CC(=CC(=C2)N)C(F)(F)F
InchIKey WWTGXYAJVXKEKL-UHFFFAOYSA-N
Inchl InChI=1S/C11H10F3N3/c1-7-5-17(6-16-7)10-3-8(11(12,13)14)2-9(15)4-10/h2-6H,15H2,1H3
IUPAC 3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)aniline
Controlled No
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Nilotinib Genotoxic Impurity 1 is a chemical impurity that is frequently present in the anti-cancer drug Nilotinib. This impurity is classified as genotoxic, meaning that it has the potential to cause mutations in DNA, potentially leading to the development of cancer. Due to its genotoxic properties, Nilotinib Genotoxic Impurity 1 is considered to be a potentially harmful substance and must be closely monitored during the production of Nilotinib. The usage of Nilotinib Genotoxic Impurity 1 is primarily to monitor the level of impurities in Nilotinib. It is essential to ensure that the drug is safe for human consumption and does not pose a significant risk to health. The amount of Nilotinib Genotoxic Impurity 1 present in Nilotinib must be kept below a certain level, as determined by regulatory authorities, to ensure that the drug is safe for use. From a chemical perspective, Nilotinib Genotoxic Impurity 1 is a derivative of Nilotinib, containing a specific chemical structure that may contribute to its genotoxic properties. It is crucial to understand the chemical properties of this impurity to ensure that it is effectively monitored and controlled during the production of Nilotinib. Overall, the usage and chemical information of Nilotinib Genotoxic Impurity 1 are essential to ensure that Nilotinib is a safe and effective drug for those who need it.

Related Compounds

Nilotinib 5-methyl isomer | Nilotinib Impurity 11 | Nilotinib Pyridine N-Oxide | Nilotinib Nitrosamine Impurity | Desmethyl nilotinib | Nilotinib EP Impurity D | Nilotinib 2-methyl isomer | Nilotinib Impurity 21 | Nilotinib Impurity 14 | Nilotinib Genotoxic Impurity 3 | Nilotinib Impurity A tetrahydrate | Nilotinib 3-Imidazolyl N-oxide | Nilotinib Impurity 3 | Nilotinib Genotoxic Impurity 2 | Nilotinib Impurity D | Nilotinib Impurity A | Nilotinib Amine impurity | Nilotinib Impurity 17 | Nilotinib Chloro impurity |

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