Nilotinib Impurity 11

Product Name Nilotinib Impurity 11
Alternate Names Nilotinib Impurities, Impurities of Nilotinib
CAT No. CS-O-15734
CAS No. 2119583-24-1
Category Impurities
Stock IN-Stock
Mol. Wt. 543.6 g/mol
Mol. For. C29H24F3N7O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Nilotinib
Therapeutic Anti-Cancer / Oncology
Smileys O=C(C1=CC=C(C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C)NC4=CC(C(F)(F)F)=CC(N5C=C(N=C5)CC)=C4
Canonical Smiles CCC1=CN(C=N1)C2=CC(=CC(=C2)NC(=O)C3=CC(=C(C=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5)C(F)(F)F
InchIKey FTJOKDORVFENBC-UHFFFAOYSA-N
Inchl InChI=1S/C29H24F3N7O/c1-3-22-16-39(17-35-22)24-13-21(29(30,31)32)12-23(14-24)36-27(40)19-7-6-18(2)26(11-19)38-28-34-10-8-25(37-28)20-5-4-9-33-15-20/h4-17H,3H2,1-2H3,(H,36,40)(H,34,37,38)
IUPAC N-[3-(4-ethylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
Controlled No
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Nilotinib Impurity 11, also known as 4-Methyl-3-nitrobenzaldehyde, is a chemical compound that is commonly used in pharmaceutical research and development. This compound is an impurity of Nilotinib, a drug used in the treatment of chronic myelogenous leukemia. Nilotinib Impurity 11 is produced as a by-product during the synthesis of Nilotinib and is known to exhibit moderate to high toxicity levels. The chemical structure of Nilotinib Impurity 11 consists of a benzene ring with a nitro group and a methyl group attached to it. This compound is a yellow crystalline solid that is sparingly soluble in water but readily soluble in organic solvents such as ethanol and methanol. Its melting point ranges from 78°C to 80°C. In terms of its usage, Nilotinib Impurity 11 is primarily used as a reference standard in analytical techniques such as high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS). It is also used as an intermediate in the synthesis of other chemical compounds. However, due to its toxicity, it is important to handle Nilotinib Impurity 11 with caution. Proper protective equipment, including gloves and a lab coat, should be worn when handling this compound. Additionally, it should be stored in a cool, dry place away from heat and sources of ignition.

Related Compounds

Nilotinib Impurity 14 | Nilotinib Genotoxic Impurity 1 | Desmethyl nilotinib | Nilotinib Impurity D | Nilotinib Impurity A | Nilotinib Genotoxic Impurity 2 | Nilotinib 5-methyl isomer | Nilotinib Impurity 3 | Nilotinib Impurity 17 | Nilotinib Impurity A tetrahydrate | Nilotinib Chloro impurity | Nilotinib 2-methyl isomer | Nilotinib Genotoxic Impurity 3 | Nilotinib Impurity 21 | Nilotinib Pyridine N-Oxide | Nilotinib Nitrosamine Impurity | Nilotinib EP Impurity D | Nilotinib Amine impurity | Nilotinib 3-Imidazolyl N-oxide |

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