CAS No.
[1051375-16-6 (Unlabeled)]
Smiles
O=C1C(N(C=C2C(NC([2H])([2H])C3=C(C([2H])=C(C=C3)F)F)=O)C[C@@]4([H])N1[C@@H](CCO4)C)=C(O)C2=O
Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(4R,12aS)-N-((2,4-difluorophenyl-3-d)methyl-d2)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
References
"Kobayashi; M, et al, Antimicrob Agents Chemother,; 55; 813 (2011); Garrido; C, et al,: Antiviral; Res,; 90; 164 (2011); Lenz; J,C,C, et al,: Exp, Opin, Invest, Drugs; 20; 537 (2011);"
Synonyms
(4R,12aS)-N-((2,4-difluorophenyl-3-d)methyl-d2)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Application Notes
"Dolutegravir Stable Isotope; Dolutegravir Deuterated, Intended for use as an internal standard for the quantification of Dolutegravir by GC- or LC-mass spectrometry."
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Dolutegravir-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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