CAS No.
[843663-66-1(Unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(αS,βR)-6-Bromo-α-[2-[di(methyl-d3)amino]ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Bedaquiline-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Bedaquiline-d6 usage and description
Bedaquiline D6 is a deuterated form of Bedaquiline, an antibiotic medication used for the treatment of tuberculosis. It is specifically used for the treatment of multi-drug resistant tuberculosis (MDR-TB) in adults. Bedaquiline D6 is a member of the diarylquinoline class of drugs and works by inhibiting the mycobacterial ATP synthase, which is essential for the energy metabolism of the bacteria.
The recommended dosage of Bedaquiline D6 is 400 mg once daily for two weeks, followed by 200 mg three times a week for the next 22 weeks. It is taken orally in the form of a tablet, with or without food. The medication should be taken at the same time every day to maintain a consistent level in the bloodstream.
As with any medication, there are potential side effects associated with Bedaquiline D6. The most common side effects include nausea, joint pain, headache, and dizziness. More serious side effects may include liver damage, cardiac arrhythmias, and increased risk of tuberculosis relapse.
In terms of chemical information, Bedaquiline D6 has a molecular formula of C32H22D6F6N4O2 and a molecular weight of 584.59 g/mol. It is a white to off-white crystalline powder that is sparingly soluble in water and soluble in ethanol. The deuterium substitution in Bedaquiline D6 provides increased stability and can help researchers track the drug's metabolism in clinical studies.
