Therapeutic Uses
Anti-Cancer / Oncology
API Family
Clarithromycin
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
Clarithromycin EP impurity C is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Clarithromycin EP impurity C usage and description
Clarithromycin EP impurity C, also known as N-desmethylclarithromycin, is an impurity of the macrolide antibiotic Clarithromycin. Clarithromycin is commonly used to treat respiratory tract infections, skin infections, and other bacterial infections. However, impurities like N-desmethylclarithromycin can affect the purity and efficacy of the final product.
N-desmethylclarithromycin is formed during the metabolism of Clarithromycin in the liver. It is a major metabolite of Clarithromycin and is excreted in the urine. N-desmethylclarithromycin has been found to exhibit some antibacterial activity but is significantly less active than Clarithromycin.
The chemical structure of N-desmethylclarithromycin is similar to that of Clarithromycin, with the exception of the absence of a methyl group on the nitrogen atom. It has a molecular weight of 697.84 g/mol and a melting point of 173-178°C.
As an impurity, N-desmethylclarithromycin should be controlled and monitored during the production of Clarithromycin to ensure the purity and quality of the final product. Analytical methods such as high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS) can be used to detect and quantify N-desmethylclarithromycin in Clarithromycin samples.
