Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
4-(4-Chlorophenyl)-4-hydroxy-N,N-di(methyl-d3)-ฮฑ,ฮฑ-diphenyl-1-piperidinebutanamide
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Loperamide-d6 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Loperamide-d6 usage and description
Loperamide is a medication used to treat diarrhea. It works by slowing down the movement of the intestines, which helps to reduce the frequency and urgency of bowel movements. Loperamide-D6 is a deuterated form of loperamide, which means that it contains six deuterium atoms in place of six hydrogen atoms. This modification is intended to improve the drug's pharmacokinetic properties by increasing its half-life and reducing its clearance rate.
The chemical formula of loperamide-D6 is C29H43D6N3O2. It has a molecular weight of 470.77 g/mol and a melting point of 223-226ยฐC. Loperamide-D6 is a white to off-white crystalline powder that is slightly soluble in water and freely soluble in ethanol.
The recommended dosage of loperamide-D6 varies depending on the severity of the diarrhea and the age of the patient. It is typically taken orally as a tablet or capsule. Loperamide-D6 should not be used in patients with a known hypersensitivity to the drug or in those with abdominal pain, constipation, or inflammatory bowel disease. It should also be used with caution in patients with liver or kidney disease, as these organs are involved in the metabolism and elimination of the drug.
In conclusion, loperamide-D6 is a useful medication for the treatment of diarrhea. Its deuterated form may offer certain pharmacokinetic advantages over the non-deuterated form, although further research is needed to fully evaluate its safety and efficacy.