Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
Camptothecin 7-Ethyl ImpurityIrinotecan EP Impurity F
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
Memantine Related Compound C is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Memantine Related Compound C usage and description
7-Ethyl Camptothecin is a synthetic analogue of Camptothecin, a natural alkaloid isolated from the bark and stem of Camptotheca acuminata. It is a potent anticancer drug that has shown efficacy against a variety of malignancies, including breast, lung, ovarian, and colon cancers. The anti-tumor activity of 7-Ethyl Camptothecin is due to its ability to inhibit topoisomerase I enzyme, which is essential for DNA replication and cell division. The drug binds to the enzyme-DNA complex, preventing the relaxation of the supercoiled DNA and causing DNA damage that results in cell death.
7-Ethyl Camptothecin is administered intravenously and has a short half-life of approximately 10 minutes. The drug is rapidly cleared from the body and is metabolized in the liver. The recommended dosage of 7-Ethyl Camptothecin varies depending on the type of cancer being treated, the patient's weight and overall health, and other factors.
Like Camptothecin, 7-Ethyl Camptothecin is a highly unstable compound that is sensitive to light, heat, and acidic conditions. The drug must be stored in a cool, dry place and protected from light until it is ready for use. In addition, 7-Ethyl Camptothecin is a potent irritant to the skin and mucous membranes, and precautions should be taken to avoid exposure during handling and administration. Despite these challenges, 7-Ethyl Camptothecin remains an important tool in the fight against cancer and continues to be studied for its potential in combination therapies and targeted drug delivery.