CAS No.
[1369773-39-6 (Unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate-d4
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 98%
Hazard Compound
No -Refer MSDS for accurate information
Sacubitril-d4 Calcium is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Sacubitril-d4 Calcium usage and description
Sacubitril D4 Calcium Salt is a deuterated form of sacubitril calcium, which is a medication used for the treatment of heart failure. Sacubitril D4 Calcium Salt is an angiotensin receptor neprilysin inhibitor (ARNI), which means it works by blocking the angiotensin II receptor and inhibiting the enzyme neprilysin. By doing so, it reduces the amount of vasoconstrictive hormones and increases the levels of vasodilatory hormones, leading to an increase in the blood flow to the heart and a decrease in cardiac workload.
The usage of Sacubitril D4 Calcium Salt is primarily for the treatment of chronic heart failure with reduced ejection fraction. It is usually taken orally, and the dosage is determined by the healthcare provider based on the patient's age, medical history, and other medications being taken. The medication is generally well-tolerated, but some side effects may occur, such as low blood pressure, kidney problems, and high potassium levels.
Chemically, Sacubitril D4 Calcium Salt is a deuterated form of sacubitril calcium, which means that it contains four deuterium atoms instead of hydrogen atoms. This modification improves the bioavailability and stability of the medication. The calcium salt form of sacubitril is used to improve the solubility and absorption of the medication in the body. Overall, Sacubitril D4 Calcium Salt is a vital medication for the treatment of heart failure, and its chemical modification enhances its therapeutic efficacy.
