CAS No.
[1426173-93-4 (freebase)]
Therapeutic Uses
Antibiotics
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one-D4 Hydrochloride
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Sitagliptin-d4 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Sitagliptin-d4 Hydrochloride usage and description
Sitagliptin D4 hydrochloride is a medication used to treat type 2 diabetes. This drug is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor, which works by increasing the levels of incretin hormones in the body. These hormones help to regulate blood sugar levels by stimulating insulin secretion and inhibiting glucagon release. Sitagliptin D4 hydrochloride is a deuterated form of sitagliptin hydrochloride, which is also used for the same purpose.
The chemical formula of Sitagliptin D4 hydrochloride is C16H15D4F6N5O.HCl, and its molecular weight is 471.78 g/mol. It is a white to off-white crystalline powder that is soluble in water and methanol. The drug is administered orally, usually once a day, with or without food.
Sitagliptin D4 hydrochloride is metabolized in the liver and excreted in the urine. It has a half-life of approximately 12.4 hours and reaches peak plasma concentrations within 1-4 hours after administration. The drug is generally well-tolerated, with common side effects including headache, nausea, and upper respiratory tract infections.
In conclusion, Sitagliptin D4 hydrochloride is a commonly used medication for the treatment of type 2 diabetes. Its chemical properties and mechanism of action make it an effective and safe option for regulating blood sugar levels in patients with this condition.
