CAS No.
89270-25-7(unlabelled)
Smiles
CC[C@H]1C(N(C)CC(N(C)[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C)C(N(C)[C@@H](CC(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])C(N(C)[C@@H](CC(C)C)C(N(C)[C@@H](C(C)C)C(N(C)C([C@H](O)[C@@H](C/C=C/C)C)C(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Storage Condition
Refer MSDS for complete information.
IUPAC Name
3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A-d6; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv.-d6; 5: PN: US6686454 SEQID-d6: 5 Claimed Protein-d6; AM 9-d6; AM 9 (Peptide)-d6; Cyclosporin A Metabolite 1-d6; Cyclosporin AM 9-d6; OL 1-d6
References
Brooks, C., et al.: Clin. Chem., 39, 457 (1993); Colombani, P., et al.: Science, 228, 337 (1985);Krönke, M., et al.: Proc. Nat. Acad. Sci., 81, 5214 (1984); Liu, J., et al.: Cell, 66, 807 (1991); Serino, F., et al.: Mol. Cell. Biochem., 122, 101 (1993)
Synonyms
3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A-d6; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv.-d6; 5: PN: US6686454 SEQID-d6: 5 Claimed Protein-d6; AM 9-d6; AM 9 (Peptide)-d6; Cyclosporin A Metabolite 1-d6; Cyclosporin AM 9-d6; OL 1-d6
Application Notes
Cyclosporin AM 9-d6 is labelled Cyclosporin AM 9 (C989405) which is a metabolite of Cyclosporin A (C988900), a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
Hazard Compound
Refer MSDS for complete information.