Product Detail
Cyclosporin AM 9-d6
Cyclosporin Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
Cyclosporin
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
Cyclosporin AM 9-d6 Product Information
Cyclosporin AM 9-d6 is listed under Stable Isotopes. It is associated with Cyclosporin and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-103626.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Cyclosporin AM 9-d6
CAS No.
89270-25-7(unlabelled)
CAT No.
CS-T-103626
Molecular Formula
C₆₂H₁₀₅D₆N₁₁O₁₃
Molecular Weight
1224.65
Category
API Family
Storage Condition
Refer MSDS for complete information.
SMILES
CC[C@H]1C(N(C)CC(N(C)[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C)C(N(C)[C@@H](CC(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])C(N(C)[C@@H](CC(C)C)C(N(C)[C@@H](C(C)C)C(N(C)C([C@H](O)[C@@H](C/C=C/C)C)C(N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
IUPAC Name
3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A-d6; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv.-d6; 5: PN: US6686454 SEQID-d6: 5 Claimed Protein-d6; AM 9-d6; AM 9 (Peptide)-d6; Cyclosporin A Metabolite 1-d6; Cyclosporin AM 9-d6; OL 1-d6
Hazard Compound
Refer MSDS for complete information.
Description
Overview
Cyclosporin AM 9-d6 is labelled Cyclosporin AM 9 (C989405) which is a metabolite of Cyclosporin A (C988900), a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
Synonyms
3-(4-Hydroxy-N-methyl-L-leucine)cyclosporin A-d6; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane Cyclic Peptide Deriv.-d6; 5: PN: US6686454 SEQID-d6: 5 Claimed Protein-d6; AM 9-d6; AM 9 (Peptide)-d6; Cyclosporin A Metabolite 1-d6; Cyclosporin AM 9-d6; OL 1-d6
Application Notes
Cyclosporin AM 9-d6 is labelled Cyclosporin AM 9 (C989405) which is a metabolite of Cyclosporin A (C988900), a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
References
Brooks, C., et al.: Clin. Chem., 39, 457 (1993); Colombani, P., et al.: Science, 228, 337 (1985);Krönke, M., et al.: Proc. Nat. Acad. Sci., 81, 5214 (1984); Liu, J., et al.: Cell, 66, 807 (1991); Serino, F., et al.: Mol. Cell. Biochem., 122, 101 (1993)
