Product Detail
Leflunomide
Leflunomide API
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
API
API Family
Leflunomide
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Leflunomide Product Information
Leflunomide is listed under API. It is associated with Leflunomide and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-01811.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Leflunomide
CAS No.
75706-12-6
CAT No.
CS-O-01811
Molecular Formula
C₁₂H₉F₃N₂O₂
Molecular Weight
270.21
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C(C1=C(C)ON=C1)NC2=CC=C(C(F)(F)F)C=C2
IUPAC Name
5-methyl-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide
Purity by HPLC
Not less than 95%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index)."
Synonyms
'Not available'
Application Notes
"An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index)."
References
"Silvestrini; B, et al,: Arzneim,-Forch,; 19; 30 (1969); Saso; L, et al,: Med, Hypoth,; 56; 114 (2001); Saso; L, et al,: Ach, Pharm, Res,; 24; 150 (2001);"
