Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propyl carbonate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
nPOC-POC Tenofovir is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
nPOC-POC Tenofovir usage and description
nPOC-POC Tenofovir is a novel prodrug of Tenofovir, which is an antiviral drug used for the treatment of HIV and hepatitis B. nPOC-POC Tenofovir is designed to improve the pharmacokinetics and bioavailability of the parent drug by increasing its solubility and stability in the body. The prodrug is rapidly converted to Tenofovir in the body, which then inhibits the reverse transcriptase enzyme of the virus, preventing the replication of the virus and slowing down the progression of the disease.
The chemical structure of nPOC-POC Tenofovir consists of two prodrug moieties, nPOC and POC, attached to the parent drug Tenofovir. These moieties improve the physicochemical properties of the drug by enhancing its water solubility and lipophilicity. The prodrug is metabolized by esterases in the body, releasing Tenofovir, which is then converted to its active form, Tenofovir diphosphate, inside the cells.
The usage of nPOC-POC Tenofovir is similar to that of Tenofovir, and it is administered orally as a tablet. The recommended dosage is 300 mg once daily for adults, and it is usually taken with food. The prodrug has been shown to be well-tolerated and safe in clinical trials, with no significant adverse effects reported. Its improved pharmacokinetic properties make it a promising candidate for the treatment of HIV and hepatitis B, especially in resource-limited settings where the availability of drugs with better bioavailability is limited.
