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CAS No.
51765-56-1
Product Code
CS-T-92564
M.F.
C₁₃H₁₁N₃O₇S
M.W.
353.31
Category
Impurity
API Family
Nimesulide
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
N-(2,4-Dinitro-6-phenoxyphenyl)methanesulfonamide
References
Pairet, M., et al.: Inflamm. Res., 47, S93 (1998), Fukutake, M., et al.: Carcinogenesis, 19, 1939 (1998), Okajima., E., et al.: Cancer Res., 58, 3028 (1998), Azab, A., et al.: Life Sci., 63, 323 (1998)
Synonyms
Not available
Application Notes
4�,6�-Dinitro-2�-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production
Purity by HPLC
98.63%
Hazard Compound
Refer MSDS for accurate information.
Overview
4�,6�-Dinitro-2�-phenoxymethanesulfonanilide, is an impurity of the drug Nimesulide (N477500), which is an antiinflammatory agent. Preferentially inhibits COX-2 over COX-1. Suppresses chemical-induced carcinogenesis in mice and rats. Inhibits LPS-induced TNF-alpha production
