Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Afatinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Afatinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Afatinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Afatinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Afatinib Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (2Z)-Afatinib-d6 | Stable Isotopes | CS-T-97835 | Not Available | Enquire |
| Afatinib-d6 | Stable Isotopes | CS-CX-00057 | 1313874-96-2 | In Stock |
| Afatinib-d6 Dimaleate | Stable Isotopes | CS-T-95339 | 1394292-94-4(Free base) | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Afatinib | API | CS-T-01429 | 850140-72-6 | In Stock |
| Afatinib dimaleate | API | CS-O-12080 | 850140-73-7 | In Stock |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (E)-4-(methylamino)but-2-enoic acid | Impurity | CS-O-60124 | 69169-63-7 | Enquire |
| Afatinib 5-hydroxypyrrolidin-2-one Impurity | Impurity | CS-EO-01168 | 2223677-58-3 | In Stock |
| Afatinib Bis-dimethylamino Impurity | Impurity | CS-O-56615 | 2414260-31-2 | Enquire |
| Afatinib dichloro impurity | Impurity | CS-ED-40634 | 2223677-63-0 | Enquire |
| Afatinib Dimer impurity | Impurity | CS-O-47043 | 2223677-65-2 | Enquire |
| Afatinib dimethyloxalamide impurity | Impurity | CS-O-47045 | 2223677-66-3 | Enquire |
| Afatinib Hydroxy impurity | Impurity | CS-O-47042 | 2223677-61-8 | Enquire |
| Afatinib Impurity 11 | Impurity | CS-O-57930 | 2413212-17-4 | Enquire |
| Afatinib Impurity 14 | Impurity | CS-O-57931 | 2413212-21-0 | Enquire |
| Afatinib Impurity 16 | Impurity | CS-EO-01556 | 2223677-60-7 | Enquire |
| Afatinib Impurity 2 | Impurity | CS-O-13086 | 1449430-45-8 | Enquire |
| Afatinib Impurity 27 | Impurity | CS-O-39522 | 618061-76-0 | Enquire |
| Afatinib Impurity 5 | Impurity | CS-O-13089 | 179552-74-0 | In Stock |
| Afatinib Impurity C | Impurity | CS-O-13077 | 945553-91-3 | Enquire |
| Afatinib Impurity H | Impurity | CS-O-13082 | 2223677-64-1 | Enquire |
| Afatinib imp-VI | Impurity | CS-O-34830 | Not Available | In Stock |
| Afatinib N-Oxide | Impurity | CS-EO-02865 | 2413212-11-8 | In Stock |
| Afatinib pyrrolidine-2,5-dione impurity | Impurity | CS-O-57964 | ---- | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)ox... | Intermediate | CS-O-13076 | 314771-76-1 | In Stock |
| trans-4-Dimethylaminocrotonic acid hydrochloride | Intermediate | CS-M-57341 | 848133-35-7 | In Stock |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Afatinib Nitroso Impurity 2 | Nitrosamine | CS-O-53320 | Not Available | In Stock |
| N-Nitroso Afatinib | Nitrosamine | CS-O-38947 | ---- | Discontinued |
Therapeutic
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Afatinib Impurity D | Therapeutic | CS-O-13078 | 1680184-59-1 | Enquire |