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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Apremilast, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Apremilast impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Apremilast-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Apremilast Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-Apremilast-d5 Stable Isotopes CS-T-100829 Not Available Enquire
Apremilast D3 Stable Isotopes CS-O-38388 Not Available In Stock
Apremilast D8 Stable Isotopes CS-O-33021 1258597-45-3 Enquire
Apremilast-d5 Stable Isotopes CS-T-48307 1258597-47-5 In Stock
rac-3’-O-Desethyl-3’-O-methyl Apremilast-d3 Stable Isotopes CS-T-100505 Not Available Enquire
rac-4’-O-Desmethyl-4’-O-ethyl Apremilast-d5 Stable Isotopes CS-T-100515 Not Available Enquire


API Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Apremilast API Standards CS-O-10092 608141-41-9 In Stock


Metabolites

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
O-Desmethyl apremilast Metabolites CS-CX-00577 1384441-38-6 In Stock


Impurities

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2-(3-ethoxy-4-4-methoyphenyl)-1-(methylsulfonyl)ethyl)arsin... Impurities CS-O-54043 1023889-29-3 Enquire
(E)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethen-1-a... Impurities CS-O-59821 1715011-38-3 Enquire
(R)-Apremilast Impurities CS-O-14904 608141-44-2 In Stock
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamin... Impurities CS-P-00642 608141-42-0 In Stock
1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone Impurities CS-T-102322 1450657-28-9 Enquire
2-((2-amino-2-(3-ethoxy-4-methoxyphenyl)ethyl)sulfonyl)ethan... Impurities CS-O-47430 2733250-84-3 Enquire
2-acetamido-6-{[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfon... Impurities CS-O-35247 Not Available Enquire
2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)ethyl)benzene Impurities CS-O-47426 2489621-73-8 Enquire
2-Ethoxy-1-methoxy-4-[(1E)-2-(methylsulfonyl)ethenyl]benzene Impurities CS-EO-00833 1831833-38-5 Enquire
3-Acetamido Apremilast ring open acid Impurity Impurities CS-O-35246 Not Available Enquire
4-Nitro Apremilast Impurities CS-O-14908 2095036-40-9 Enquire
5-Acetamide Apremilast Impurities CS-O-14907 2201974-01-6 Enquire
Apremilast 2-hydroxyethyl-sulfonyl impurity Impurities CS-O-47428 Not Available Enquire
Apremilast 3-amino phthalimide ring open isomer impurity-1 Impurities CS-O-54117 Not Available Enquire
Apremilast Degradation Impurity -2 Impurities CS-O-47078 Not Available Enquire
Apremilast Des Acetyl Impurity Impurities CS-O-14905 635705-72-5 In Stock
Apremilast Desoxo impurity Impurities CS-EO-00824 Not Available Enquire
Apremilast Diethoxy Analog Impurities CS-O-58675 Not Available Enquire
Apremilast Dimer Impurities CS-O-14906 Not Available Enquire
Apremilast Dimer Impurities CS-EO-01318 1802246-60-1 Enquire
Apremilast Dimethoxy Analog Impurities CS-O-58454 1809089-51-7 In Stock
Apremilast Enantiomer Impurities CS-SN-00134 253168-86-4 Enquire
Apremilast Impurity 10 Impurities CS-O-16949 2096492-41-8 In Stock
Apremilast Impurity 14 Impurities CS-O-58626 2487573-05-5 Enquire
Apremilast Impurity 15 Impurities CS-EO-00834 2096492-43-0 Enquire
Apremilast Impurity 17 Impurities CS-EO-02882 2487573-01-1 Enquire
Apremilast Impurity 18 Impurities CS-EO-03088 2055542-18-0 Enquire
Apremilast Impurity 2 Impurities CS-P-00643 608141-44-2 Enquire
Apremilast Impurity 77 Impurities CS-P-09086 1912443-44-7 In Stock
Apremilast Impurity 8 Impurities CS-EO-00835 2096492-44-1 Enquire
Apremilast Impurity B Impurities CS-O-15684 15371-06-9 In Stock
Apremilast Impurity C Impurities CS-P-08194 Not Available Enquire
Apremilast impurity D Impurities CS-O-15764 253168-87-5 In Stock
Apremilast Impurity F Impurities CS-P-00641 Not Available Enquire
Apremilast Impurity H Impurities CS-O-13860 253168-94-4 In Stock
Apremilast Isopropyl alcohol Impurity Impurities CS-O-47427 Not Available Enquire
Apremilast Olifin Amine Impurities CS-O-58627 1450657-31-4 Enquire
Apremilast pseudo dimer impurity Impurities CS-O-47429 Not Available Enquire
Desacetyl Apremilast benzoic acid Impurity Impurities CS-O-49080 Not Available In Stock
Desoxo Apremilast Impurities CS-T-93704 Not Available Enquire
Diethoxy Rac-Apremilast Impurity Impurities CS-O-46940 2448678-64-4 In Stock
Methyl Hydroxy Apremilast Impurities CS-O-14909 Enquire
N-Deacetyl-2-carboxy-(seco-phthalimido) Apremilast Impurities CS-O-50394 Not Available Enquire
N-Desacetyl O4-Desmethyl Apremilast Impurities CS-T-88348 1384440-16-7 Enquire
N-Desacetyl O4-Desmethyl O3-Desethyl Apremilast Impurities CS-T-88483 1384439-80-8 Enquire
O4-Desmethyl O3-Desethyl Apremilast Impurities CS-T-89052 1384439-79-5 Enquire


Intermediates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-Ethoxy-4-methoxybenzaldehyde Intermediates CS-M-18021 1131-52-8 Enquire
Apremilast 2-acetamido benzoic acid Intermediates CS-T-64452 1809170-71-5 Enquire
N-Desacetyl-N-formyl Apremilast Intermediates CS-T-88622 2077897-94-8 Enquire
O3-Desethyl Apremilast Intermediates CS-T-88675 1384967-20-7 In Stock


Glucuronides

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
O-Desmethyl Apremilast Glucuronide Glucuronides CS-O-37681 1384814-89-4 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)ethanone Fine Chemicals CS-O-59811 1282933-35-0 Enquire
3-Acetamidophthalic Anhydride Fine Chemicals CS-T-47149 6296-53-3 In Stock
3-Hydroxy-4-Methoxy Benzonitrile Fine Chemicals CS-M-57090 52805-46-6 In Stock