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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Apremilast, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Apremilast impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Apremilast-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Apremilast Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-Apremilast-d5 Stable Isotopes CS-T-100829 Not Available Enquire
Apremilast-d3 Stable Isotopes CS-O-38388 1386387-95-6 In Stock
Apremilast-d5 Stable Isotopes CS-T-48307 1258597-47-5 In Stock
rac-3’-O-Desethyl-3’-O-methyl Apremilast-d3 Stable Isotopes CS-T-100505 Not Available Enquire
rac-4’-O-Desmethyl-4’-O-ethyl Apremilast-d5 Stable Isotopes CS-T-100515 Not Available Enquire
rac-4’-O-Ethyl-3’-O-methyl Apremilast-d5 Stable Isotopes CS-T-100344 2714417-51-1 Enquire
Apremilast D8 Stable Isotopes CS-O-33021 1258597-45-3 Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Apremilast API CS-O-10092 608141-41-9 In Stock


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
O-Desmethyl apremilast Metabolite CS-CX-00577 1384441-38-6 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(2-(3-ethoxy-4-4-methoyphenyl)-1-(methylsulfonyl)ethyl)arsin... Impurity CS-O-54043 ---- Enquire
(E)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethen-1-a... Impurity CS-O-59821 1715011-38-3 Enquire
(R)-Apremilast Impurity CS-O-14904 608141-44-2 In Stock
(S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamin... Impurity CS-P-00642 608141-42-0 In Stock
1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone Impurity CS-T-102322 1450657-28-9 Enquire
2-((2-amino-2-(3-ethoxy-4-methoxyphenyl)ethyl)sulfonyl)ethan... Impurity CS-O-47430 2733250-84-3 Enquire
2-ethoxy-1-methoxy-4-(2-(methylsulfonyl)ethyl)benzene Impurity CS-O-47426 2489621-73-8 Enquire
3-Nitrophthalic Acid Impurity CS-T-59602 603-11-2 In Stock
4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methyl sulfonyl)e... Impurity CS-O-34485 253168-83-1 In Stock
Apremilast 2-hydroxyethyl-sulfonyl impurity Impurity CS-O-47428 Not Available Enquire
Apremilast 3-amino phthalimide ring open isomer impurity-1 Impurity CS-O-54117 ---- Enquire
Apremilast Degradation Impurity -2 Impurity CS-O-47078 Not Available Enquire
Apremilast Des Acetyl Impurity Impurity CS-O-14905 635705-72-5 In Stock
Apremilast Diethoxy Analog Impurity CS-O-58675 ---- Enquire
Apremilast Dimer Impurity CS-EO-01318 1802246-60-1 Enquire
Apremilast Dimethoxy Analog Impurity CS-O-58454 1809089-51-7 In Stock
Apremilast Enantiomer Impurity CS-SN-00134 253168-86-4 Enquire
Apremilast Impurity 10 Impurity CS-O-16949 2096492-41-8 In Stock
Apremilast Impurity 14 Impurity CS-O-58626 2487573-05-5 Enquire
Apremilast Impurity 17 Impurity CS-EO-02882 2487573-01-1 Enquire
Apremilast Impurity 18 Impurity CS-EO-03088 2055542-18-0 Enquire
Apremilast Impurity 77 Impurity CS-P-09086 1912443-44-7 In Stock
Apremilast Impurity B Impurity CS-O-15684 15371-06-9 In Stock
Apremilast Impurity C Impurity CS-P-08194 Not Available Enquire
Apremilast impurity D Impurity CS-O-15764 253168-87-5 In Stock
Apremilast Impurity H Impurity CS-O-13860 253168-94-4 In Stock
Apremilast Isopropyl alcohol Impurity Impurity CS-O-47427 Not Available Enquire
Apremilast Olifin Amine Impurity CS-O-58627 1450657-31-4 Enquire
Apremilast pseudo dimer impurity Impurity CS-O-47429 Not Available Enquire
Apremilast Related Compound E Impurity CS-O-58458 ---- Enquire
Desacetyl Apremilast benzoic acid Impurity Impurity CS-O-49080 Not Available In Stock
Diethoxy Rac-Apremilast Impurity Impurity CS-O-46940 2448678-64-4 In Stock
N-acetyl amine impurity Impurity CS-O-48551 Not Available Enquire
N-Deacetyl-2-carboxy-(seco-phthalimido) Apremilast Impurity CS-O-50394 ---- Enquire
(S)-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)... Impurity CS-O-40103 2077897-93-7 Enquire
2-acetamido-6-{[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfon... Impurity CS-O-35247 Not Available Enquire
3-Acetamido Apremilast ring open acid Impurity Impurity CS-O-35246 Not Available Enquire
4-Nitro Apremilast Impurity CS-O-14908 2095036-40-9 Enquire
5-Acetamide Apremilast Impurity CS-O-14907 2201974-01-6 Enquire
5-amino desacetamido Apremilast Impurity CS-EO-01649 Not Available Enquire
5-Nitro desacetamido Apremilast Impurity CS-EO-01650 Not Available Enquire
Apremilast 2-acetamido benzoic acid Impurity CS-T-64452 1809170-71-5 Enquire
Apremilast Acetamido Sulfone Impurity Impurity CS-O-42232 2097600-16-1 Enquire
Apremilast Desoxo impurity Impurity CS-EO-00824 Not Available Enquire
Apremilast Impurity 15 Impurity CS-EO-00834 2096492-43-0 Enquire
Apremilast Impurity 8 Impurity CS-EO-00835 2096492-44-1 Enquire
Apremilast Impurity F Impurity CS-P-00641 Not Available Enquire
Desoxo Apremilast Impurity CS-T-93704 Not Available Enquire
Methyl Hydroxy Apremilast Impurity CS-O-14909 Enquire
N-Desacetyl O4-Desmethyl Apremilast Impurity CS-T-88348 1384440-16-7 Enquire
N-Desacetyl O4-Desmethyl O3-Desethyl Apremilast Impurity CS-T-88483 1384439-80-8 Enquire
O4-Desmethyl O3-Desethyl Apremilast Impurity CS-T-89052 1384439-79-5 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamin... Intermediate CS-O-13861 608141-43-1 In Stock
O3-Desethyl Apremilast Intermediate CS-T-88675 1384967-20-7 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
O-Desmethyl Apremilast Glucuronide Glucuronide CS-O-37681 1384814-89-4 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-(3,4-dimethoxyphenyl)-2-(methylsulfonyl)ethanone Fine Chemicals CS-O-59811 1282933-35-0 Enquire
3-Acetamidophthalic Anhydride Fine Chemicals CS-T-47149 6296-53-3 In Stock
3-Hydroxy-4-Methoxy Benzonitrile Fine Chemicals CS-M-57090 52805-46-6 In Stock


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Apremilast Nitroso Impurity 3 Nitrosamine CS-EO-03969 Not Available Enquire
N-Nitroso Apremilast Nitrosamine CS-EO-02623 ---- In Stock