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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Aprepitant, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Aprepitant impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Aprepitant-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Aprepitant Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 Stable Isotopes CS-T-97655 Not Available Enquire
Aprepitant Benzyl Intermediate-d4 Stable Isotopes CS-O-49156 2377328-01-1 (Unlabelled) In Stock
Aprepitant Intermediate-d4 Stable Isotopes CS-O-49157 171338-27-5 (Unlabelled) In Stock
Aprepitant-d4 Stable Isotopes CS-O-06411 1133387-60-6 In Stock
Aprepitant-d4 N-Oxide Stable Isotopes CS-T-103829 172673-23-3(unlabelled) Enquire
ent-Aprepitant-13C15N2 Stable Isotopes CS-T-97789 Not Available Enquire
Fosaprepitant-13C,15N3 Dimeglumine Stable Isotopes CS-T-97493 Not Available Enquire
Fosaprepitant-d4 Dimeglumine Stable Isotopes CS-O-06636 265121-04-8(Unlabeled) In Stock
N-Nitroso Aprepitant intermediate D4 Stable Isotopes CS-O-52326 171338-27-5 (Unlabelled) Enquire
rac-Aprepitant-D4 Stable Isotopes CS-SN-00003 2748471-42-1 Enquire
2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... Stable Isotopes CS-T-101797 1217645-68-5 Enquire
Aprepitant 13C6 Stable Isotopes CS-EK-01190 170729-80-3 unlabeled Enquire
Aprepitant-13C2,d2 (Major) Stable Isotopes CS-T-66214 1217676-37-3 Enquire
Fosaprepitant 13C6 Stable Isotopes CS-EK-01741 172673-20-0 unlabeled Enquire
Fosaprepitant D4 Stable Isotopes CS-O-03674 172673-20-0 (Unlabeled) Enquire
Fosaprepitant dimeglumine 13C6 Stable Isotopes CS-EK-01820 265121-04-8 unlabeled Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Aprepitant API CS-O-11601 170729-80-3 In Stock
Fosaprepitant Dimeglumine API CS-O-30923 265121-04-8 In Stock
Fosaprepitant Potassium salt API CS-EO-03579 172822-03-6 Enquire
Fosaprepitant API CS-T-24784 172673-20-0 In Stock


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Aprepitant M2 Metabolite (1R, 2R, 3R)-Isomer Metabolite CS-EO-03325 380499-06-9 Enquire
Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer Metabolite CS-EO-03326 170902-80-4 Enquire
Aprepitant M2 Metabolite (1S, 2R, 3R)-Isomer Metabolite CS-EO-03327 1242175-36-5 Enquire
Aprepitant N-Oxide Metabolite CS-O-15660 172673-23-3 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1R,2R,2R Aprepitant Impurity CS-T-04043 1148113-53-4 Enquire
1S,2S,3R-Aprepitant Impurity CS-T-04044 172822-29-6 In Stock
5-({[(1R)-1-(4-fluorophenyl)-2-hydroxyethyl]amino}methyl)-2,... Impurity CS-O-47245 Not Available Enquire
Aprepitant EP Impurity A Impurity CS-T-14763 170729-76-7 Enquire
Aprepitant EP Impurity B Impurity CS-P-00645 2348441-62-1 Enquire
Aprepitant EP Impurity C Impurity CS-EO-00264 2348441-63-2 Enquire
Aprepitant Impurity 15 Impurity CS-T-95910 1447693-83-5 Enquire
Aprepitant Impurity 68 Impurity CS-O-60244 ---- Enquire
Aprepitant Impurity 95 Impurity CS-O-60242 134542-35-1 Enquire
Aprepitant Impurity 96 Impurity CS-O-60243 885955-61-3 Enquire
Aprepitant M3 Metabolite (1R, 5S, 6R)-Isomer Impurity CS-EO-03052 419574-04-2 Enquire
Fosaprepitant Dibenzyl Ester Impurity CS-T-76464 265121-01-5 Enquire
Fosaprepitant Dimeglumine Impurity F (Dimeglumine salt) Impurity CS-EO-04064 2035475-11-5 Enquire
Fosaprepitant Impurity 1 Impurity CS-EO-02756 1185503-00-7 Enquire
Fosaprepitant Morpholin Impurity Impurity CS-EO-03578 1242175-41-2 Enquire
Fosaprepitant N-oxide Impurity CS-T-93417 ---- Enquire
Fosaprepitant(1S,2R,3S)isomer Impurity CS-O-45670 Not Available Enquire
(1S,2R,3S)-Aprepitant Impurity CS-P-07152 170902-81-5 Enquire
1R,2S,3R Aprepitant Impurity CS-O-13151 1185502-97-9 Enquire
1R,2S,3S Aprepitant Impurity CS-O-13149 172822-28-5 Enquire
1S,2R,3R Aprepitant Impurity CS-O-13148 1242175-34-3 Enquire
1S,2R,3S Aprepitant Impurity CS-O-13152 170901-81-5 Enquire
1S,2S,3S Aprepitant Impurity CS-O-13150 1242175-40-1 Enquire
2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... Impurity CS-T-07625 171338-27-5 Enquire
2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... Impurity CS-T-07627 170729-79-0 Enquire
Aprepitant Impurity 1 Hydrochloride Impurity CS-P-07153 327623-37-0 (free base) Enquire
Aprepitant Impurity 13 Impurity CS-O-37096 2206135-44-4 Enquire
Aprepitant Impurity 14 Impurity CS-P-08704 2204442-75-9 Enquire
Aprepitant Impurity 2 Impurity CS-P-00644 Not Available Enquire
Aprepitant Impurity 4 Impurity CS-P-08701 1333998-21-2 Enquire
Aprepitant Impurity 7 Impurity CS-P-08702 874460-46-5 Enquire
Aprepitant Impurity 8 Impurity CS-P-08703 1333998-27-8 Enquire
Aprepitant Impurity 9 Impurity CS-P-07155 219821-37-1 Enquire
Aprepitant Impurity B Enantiomer Hydrochloride Impurity CS-P-07154 183901-47-5 Enquire
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1’R)-Aprepitant Impurity CS-T-88323 1185503-48-3 Enquire
Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1’S)-Aprepitant Impurity CS-T-88653 327623-37-0 Enquire
Desfluoro Fosaprepitant Impurity CS-O-14055 Not Available Enquire
Fosaprepitant Benzyl Ester Impurity CS-P-08003 889852-02-2 Enquire
Fosaprepitant Diastereomer Impurity CS-O-36242 1523569-90-5 Enquire
Fosaprepitant Dimeglumine Desfluoro impurity Impurity CS-O-36244 Not Available Enquire
Fosaprepitant dimeglumine Diastereomer Impurity Impurity CS-O-34114 Not Available Enquire
Fosaprepitant Dimeglumine Impurity D Impurity CS-O-32650 Not Available Enquire
Fosaprepitant Dimeglumine Impurity E Impurity CS-O-32651 Not Available Enquire
Fosaprepitant Dimeglumine Impurity F Impurity CS-EO-00495 2035475-10-4 Enquire
Fosaprepitant Dimeglumine isomer(2S,3R) Impurity CS-O-36243 1523569-87-0 Enquire
Fosaprepitant dimeglumine stereochemical purity standard Impurity CS-O-35350 Not Available Enquire
Fosaprepitant Enantiomer Impurity CS-EO-00570 1523569-86-9 Enquire
Fosaprepitant Impurity 2 Impurity CS-EO-00553 Not Available Enquire
Fosaprepitant Impurity 4 Impurity CS-EO-00569 Not Available Enquire
Fosaprepitant Impurity 6 Impurity CS-EO-00571 172822-01-4 Enquire
Fosaprepitant Impurity D Impurity CS-O-43220 Not Available Enquire
Fosaprepitant Impurity E Impurity CS-O-43221 Not Available Enquire
Fosaprepitant Impurity F Impurity CS-O-35351 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-methoxy carbonyl-2-chloroacetamidrazone Intermediate CS-T-32267 155742-64-6 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Aprepitant glucuronide Glucuronide CS-T-102309 Not Available Enquire