Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Aprepitant, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Aprepitant impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Aprepitant-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Aprepitant-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Aprepitant Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 4-Defluoro-4-(p-fluorophenyl)aprepitant-13C, 15N2 | Stable Isotopes | CS-T-97655 | Not Available | Enquire |
| Aprepitant Benzyl Intermediate-d4 | Stable Isotopes | CS-O-49156 | 2377328-01-1 (Unlabelled) | In Stock |
| Aprepitant Intermediate-d4 | Stable Isotopes | CS-O-49157 | 171338-27-5 (Unlabelled) | In Stock |
| Aprepitant-d4 | Stable Isotopes | CS-O-06411 | 1133387-60-6 | In Stock |
| Aprepitant-d4 N-Oxide | Stable Isotopes | CS-T-103829 | 172673-23-3(unlabelled) | Enquire |
| ent-Aprepitant-13C15N2 | Stable Isotopes | CS-T-97789 | Not Available | Enquire |
| Fosaprepitant-13C,15N3 Dimeglumine | Stable Isotopes | CS-T-97493 | Not Available | Enquire |
| Fosaprepitant-d4 Dimeglumine | Stable Isotopes | CS-O-06636 | 265121-04-8(Unlabeled) | In Stock |
| N-Nitroso Aprepitant intermediate D4 | Stable Isotopes | CS-O-52326 | 171338-27-5 (Unlabelled) | Enquire |
| rac-Aprepitant-D4 | Stable Isotopes | CS-SN-00003 | 2748471-42-1 | Enquire |
| 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... | Stable Isotopes | CS-T-101797 | 1217645-68-5 | Enquire |
| Aprepitant 13C6 | Stable Isotopes | CS-EK-01190 | 170729-80-3 unlabeled | Enquire |
| Aprepitant-13C2,d2 (Major) | Stable Isotopes | CS-T-66214 | 1217676-37-3 | Enquire |
| Fosaprepitant 13C6 | Stable Isotopes | CS-EK-01741 | 172673-20-0 unlabeled | Enquire |
| Fosaprepitant D4 | Stable Isotopes | CS-O-03674 | 172673-20-0 (Unlabeled) | Enquire |
| Fosaprepitant dimeglumine 13C6 | Stable Isotopes | CS-EK-01820 | 265121-04-8 unlabeled | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Aprepitant | API | CS-O-11601 | 170729-80-3 | In Stock |
| Fosaprepitant Dimeglumine | API | CS-O-30923 | 265121-04-8 | In Stock |
| Fosaprepitant Potassium salt | API | CS-EO-03579 | 172822-03-6 | Enquire |
| Fosaprepitant | API | CS-T-24784 | 172673-20-0 | In Stock |
Metabolite
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Aprepitant M2 Metabolite (1R, 2R, 3R)-Isomer | Metabolite | CS-EO-03325 | 380499-06-9 | Enquire |
| Aprepitant M2 Metabolite (1R, 2S, 3S)-Isomer | Metabolite | CS-EO-03326 | 170902-80-4 | Enquire |
| Aprepitant M2 Metabolite (1S, 2R, 3R)-Isomer | Metabolite | CS-EO-03327 | 1242175-36-5 | Enquire |
| Aprepitant N-Oxide | Metabolite | CS-O-15660 | 172673-23-3 | In Stock |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 1R,2R,2R Aprepitant | Impurity | CS-T-04043 | 1148113-53-4 | Enquire |
| 1S,2S,3R-Aprepitant | Impurity | CS-T-04044 | 172822-29-6 | In Stock |
| 5-({[(1R)-1-(4-fluorophenyl)-2-hydroxyethyl]amino}methyl)-2,... | Impurity | CS-O-47245 | Not Available | Enquire |
| Aprepitant EP Impurity A | Impurity | CS-T-14763 | 170729-76-7 | Enquire |
| Aprepitant EP Impurity B | Impurity | CS-P-00645 | 2348441-62-1 | Enquire |
| Aprepitant EP Impurity C | Impurity | CS-EO-00264 | 2348441-63-2 | Enquire |
| Aprepitant Impurity 15 | Impurity | CS-T-95910 | 1447693-83-5 | Enquire |
| Aprepitant Impurity 68 | Impurity | CS-O-60244 | ---- | Enquire |
| Aprepitant Impurity 95 | Impurity | CS-O-60242 | 134542-35-1 | Enquire |
| Aprepitant Impurity 96 | Impurity | CS-O-60243 | 885955-61-3 | Enquire |
| Aprepitant M3 Metabolite (1R, 5S, 6R)-Isomer | Impurity | CS-EO-03052 | 419574-04-2 | Enquire |
| Fosaprepitant Dibenzyl Ester | Impurity | CS-T-76464 | 265121-01-5 | Enquire |
| Fosaprepitant Dimeglumine Impurity F (Dimeglumine salt) | Impurity | CS-EO-04064 | 2035475-11-5 | Enquire |
| Fosaprepitant Dimeglumine Stereochemical Purity Standard | Impurity | CS-O-35350 | 265121-04-8 | Enquire |
| Fosaprepitant Impurity 1 | Impurity | CS-EO-02756 | 1185503-00-7 | Enquire |
| Fosaprepitant Morpholin Impurity | Impurity | CS-EO-03578 | 1242175-41-2 | Enquire |
| Fosaprepitant N-oxide | Impurity | CS-T-93417 | ---- | Enquire |
| Fosaprepitant(1S,2R,3S)isomer | Impurity | CS-O-45670 | Not Available | Enquire |
| (1S,2R,3S)-Aprepitant | Impurity | CS-P-07152 | 170902-81-5 | Enquire |
| 1R,2S,3R Aprepitant | Impurity | CS-O-13151 | 1185502-97-9 | Enquire |
| 1R,2S,3S Aprepitant | Impurity | CS-O-13149 | 172822-28-5 | Enquire |
| 1S,2R,3R Aprepitant | Impurity | CS-O-13148 | 1242175-34-3 | Enquire |
| 1S,2R,3S Aprepitant | Impurity | CS-O-13152 | 170901-81-5 | Enquire |
| 1S,2S,3S Aprepitant | Impurity | CS-O-13150 | 1242175-40-1 | Enquire |
| 2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... | Impurity | CS-T-07625 | 171338-27-5 | Enquire |
| 2-(R)-[1-(S)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-f... | Impurity | CS-T-07627 | 170729-79-0 | Enquire |
| Aprepitant Impurity 1 Hydrochloride | Impurity | CS-P-07153 | 327623-37-0 (free base) | Enquire |
| Aprepitant Impurity 13 | Impurity | CS-O-37096 | 2206135-44-4 | Enquire |
| Aprepitant Impurity 14 | Impurity | CS-P-08704 | 2204442-75-9 | Enquire |
| Aprepitant Impurity 2 | Impurity | CS-P-00644 | Not Available | Enquire |
| Aprepitant Impurity 4 | Impurity | CS-P-08701 | 1333998-21-2 | Enquire |
| Aprepitant Impurity 7 | Impurity | CS-P-08702 | 874460-46-5 | Enquire |
| Aprepitant Impurity 8 | Impurity | CS-P-08703 | 1333998-27-8 | Enquire |
| Aprepitant Impurity 9 | Impurity | CS-P-07155 | 219821-37-1 | Enquire |
| Aprepitant Impurity B Enantiomer Hydrochloride | Impurity | CS-P-07154 | 183901-47-5 | Enquire |
| Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1’R)-Aprepitant | Impurity | CS-T-88323 | 1185503-48-3 | Enquire |
| Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1’S)-Aprepitant | Impurity | CS-T-88653 | 327623-37-0 | Enquire |
| Desfluoro Fosaprepitant | Impurity | CS-O-14055 | Not Available | Enquire |
| Fosaprepitant Benzyl Ester | Impurity | CS-P-08003 | 889852-02-2 | Enquire |
| Fosaprepitant Diastereomer | Impurity | CS-O-36242 | 1523569-90-5 | Enquire |
| Fosaprepitant Dimeglumine Desfluoro impurity | Impurity | CS-O-36244 | Not Available | Enquire |
| Fosaprepitant dimeglumine Diastereomer Impurity | Impurity | CS-O-34114 | Not Available | Enquire |
| Fosaprepitant Dimeglumine Impurity D | Impurity | CS-O-32650 | Not Available | Enquire |
| Fosaprepitant Dimeglumine Impurity E | Impurity | CS-O-32651 | Not Available | Enquire |
| Fosaprepitant Dimeglumine Impurity F | Impurity | CS-EO-00495 | 2035475-10-4 | Enquire |
| Fosaprepitant Dimeglumine isomer(2S,3R) | Impurity | CS-O-36243 | 1523569-87-0 | Enquire |
| Fosaprepitant Enantiomer | Impurity | CS-EO-00570 | 1523569-86-9 | Enquire |
| Fosaprepitant Impurity 2 | Impurity | CS-EO-00553 | Not Available | Enquire |
| Fosaprepitant Impurity 4 | Impurity | CS-EO-00569 | Not Available | Enquire |
| Fosaprepitant Impurity 6 | Impurity | CS-EO-00571 | 172822-01-4 | Enquire |
| Fosaprepitant Impurity D | Impurity | CS-O-43220 | Not Available | Enquire |
| Fosaprepitant Impurity E | Impurity | CS-O-43221 | Not Available | Enquire |
| Fosaprepitant Impurity F | Impurity | CS-O-35351 | Not Available | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| N-methoxy carbonyl-2-chloroacetamidrazone | Intermediate | CS-T-32267 | 155742-64-6 | In Stock |
Glucuronide
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Aprepitant glucuronide | Glucuronide | CS-T-102309 | Not Available | Enquire |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(... | Nitrosamine | CS-O-40098 | Not Available | Enquire |
| N-nitroso destriazol Aprepitant | Nitrosamine | CS-O-52327 | Not Available | Enquire |
| N-Nitroso Fosaprepitant | Nitrosamine | CS-O-51676 | Not Available | Enquire |
| N-NITROSO-2-HYDROXYETHYL BENZYLAMINE | Nitrosamine | CS-O-40099 | 77817-40-4 | In Stock |