Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Macitentan, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Macitentan impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Macitentan-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Macitentan-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Macitentan Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Macitentan ACT-132577-d4 | Stable Isotopes | CS-BU-00057 | 2748196-51-0 | In Stock |
| Macitentan-d4 | Stable Isotopes | CS-O-14938 | 1258428-05-5 | In Stock |
| O-Desbromo-pyrimidinyl Macitentan-d4 | Stable Isotopes | CS-T-100538 | Not Available | Enquire |
| Macitentan 13C2 D4 | Stable Isotopes | CS-SN-00049 | Not Available | Enquire |
| Macitentan Metabolite 13C2, 2H4 | Stable Isotopes | CS-SN-00048 | Not Available | Enquire |
API
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Aprocitentan | API | CS-T-16586 | 1103522-45-7 | In Stock |
| Macitentan | API | CS-T-57357 | 441798-33-0 | In Stock |
Impurity
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 2-[[6-Amino-5-(4-bromophenyl)-4-pyrimidinyl]oxy]-ethanol | Impurity | CS-TA-06611 | 2211059-05-9 | Enquire |
| 5-(Desbromophenyl)-5-Phenyl-Macitentan | Impurity | CS-O-59297 | 2300968-87-8 | Enquire |
| 5-Bromo-2-(2-chloroethoxy)pyrimidine | Impurity | CS-O-40899 | 2365406-84-2 | Enquire |
| 5-Bromo-2-hydroxypyrimidine | Impurity | CS-T-08323 | 38353-06-9 | Enquire |
| 5-Des-Bromo-Macitentan | Impurity | CS-O-59292 | 2211059-00-4 | Enquire |
| DiDesbromo Dichloro Macitentan impurity | Impurity | CS-O-40902 | Not Available | Enquire |
| Macitentan ACT-373898 | Impurity | CS-O-14882 | 1433875-14-9 | In Stock |
| Macitentan Impurity 1 | Impurity | CS-O-14876 | 1433875-21-8 | Enquire |
| Macitentan Impurity 10 | Impurity | CS-O-59285 | ---- | Enquire |
| Macitentan Impurity 11 | Impurity | CS-O-59291 | 2108101-97-7 | Enquire |
| Macitentan Impurity 12 | Impurity | CS-O-59467 | 1642873-04-8 | Enquire |
| Macitentan Impurity 13 | Impurity | CS-O-56880 | 3974-18-3 | Enquire |
| Macitentan Impurity 16 | Impurity | CS-O-59278 | 2211054-17-8 | Enquire |
| Macitentan Impurity 17 | Impurity | CS-O-59277 | 2211054-46-3 | Enquire |
| Macitentan Impurity 2 | Impurity | CS-O-14877 | 2211054-90-7 | Enquire |
| Macitentan Impurity 20 | Impurity | CS-O-60251 | ---- | Enquire |
| Macitentan Impurity 28 | Impurity | CS-O-59299 | 2443747-63-3 | Enquire |
| Macitentan Impurity 32 | Impurity | CS-O-58974 | 2211969-79-6 | Enquire |
| Macitentan Impurity 47 | Impurity | CS-O-40901 | 2365406-87-5 | Enquire |
| Macitentan Impurity 49 | Impurity | CS-O-59287 | 2365406-86-4 | Enquire |
| Macitentan Impurity 6 | Impurity | CS-O-59289 | ---- | Enquire |
| Macitentan Impurity 9 | Impurity | CS-O-47854 | 2518002-08-7 | Enquire |
| Macitentan Impurity C | Impurity | CS-T-95882 | 441798-36-3 | In Stock |
| Macitentan Isopropyl Impurity | Impurity | CS-EO-03228 | Not Available | Enquire |
| Macitentan Pyrimidine N-Propyl | Impurity | CS-O-45760 | Not Available | Enquire |
| Macitentan Stage-I Hydroxy Impurity | Impurity | CS-O-53793 | 2365406-85-3 | Enquire |
| Macitentan Sulfamide Dimer | Impurity | CS-O-16882 | 2089065-77-8 | Enquire |
| N-[5-(4-Hydroxyphenyl)-6-hydroxy-4-pyrimidinyl]-N'-propylsul... | Impurity | CS-O-59286 | ---- | Enquire |
| O-Desbromo-Pyrimidinyl Macitentan | Impurity | CS-T-73903 | 1393813-43-8 | Enquire |
| 2,2-dimethyl-N-(propylsulfamoyl)propanamide | Impurity | CS-O-14875 | 1393813-40-5 | Enquire |
| 5-(4-Bromophenyl)-6-(2-chloroethoxy)pyrimidin-4-amine | Impurity | CS-O-40900 | Not Available | Enquire |
| 5-(4-bromophenyl)-6-hydroxypyrimidin-4(3H)-one | Impurity | CS-O-14734 | 706811-25-8 | Enquire |
| Hydroxy N-Propyl Impurity | Impurity | CS-EO-00618 | Not Available | Enquire |
| Macitentan Impurity 22 | Impurity | CS-EO-01548 | Not Available | Enquire |
| Macitentan Impurity 3 | Impurity | CS-O-14878 | Not Available | Enquire |
| Macitentan Impurity 39 | Impurity | CS-P-09226 | 2300968-85-6 | Enquire |
| Macitentan Impurity 4 | Impurity | CS-O-14879 | Enquire | |
| Macitentan Impurity 5 | Impurity | CS-O-14880 | 441798-25-0 | Enquire |
| Macitentan Impurity A | Impurity | CS-EA-00002 | 441798-25-0 | Enquire |
| N-Despropyl-N-Ethyl Macitentan | Impurity | CS-O-14881 | 441796-13-0 | Enquire |
| N-Despropyl-N-methyl Macitentan | Impurity | CS-T-89056 | 441798-25-0 | Enquire |
| Pyrimidine N-propyl impurity | Impurity | CS-O-16881 | Not Available | Enquire |
| S-Despropylamino S-Methyl Macitentan | Impurity | CS-T-89014 | 556796-88-4 | Enquire |
Intermediate
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 5-(4-bromophenyl)-4,6-dichloropyrimidine | Intermediate | CS-O-14737 | 146533-41-7 | In Stock |
Fine Chemicals
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Chlordisulfurylisocyanat | Fine Chemicals | CS-O-40851 | 63549-29-1 | Enquire |
| N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N-propyl-Sulfam... | Fine Chemicals | CS-MM-62517 | 1393813-42-7 | Enquire |
Nitrosamine
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Macitentan Hydroxy N-Nitroso N-Propyl Impurity | Nitrosamine | CS-O-50177 | Not Available | Enquire |
| Macitentan Pyrimidine N-Nitroso N-Propyl Impurity | Nitrosamine | CS-O-50176 | Not Available | Enquire |
| N-Nitroso Macitentan | Nitrosamine | CS-O-44515 | ---- | Enquire |
| N-Nitroso Macitentan Dimer Impurity | Nitrosamine | CS-O-44516 | Not Available | Enquire |
| N-Nitroso Macitentan Impurity 19 | Nitrosamine | CS-O-44517 | Not Available | Enquire |
| N-Nitroso Macitentan Impurity 21 | Nitrosamine | CS-O-44518 | Not Available | Enquire |