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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Sitagliptin, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Sitagliptin impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Sitagliptin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Sitagliptin Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
ent-Sitagliptin-d4 Phosphate Stable Isotopes CS-T-97171 Not Available Enquire
Formyl sitagliptin d4 Stable Isotopes CS-O-46149 Not Available Enquire
N-Acetyl Sitagliptin-d3 Stable Isotopes CS-T-64537 1795785-80-6 In Stock
Nitroso-STG-19 (Sitagliptin)-15ND4 Stable Isotopes CS-T-104129 Not Available Enquire
Nitroso-STG-19 (Sitagliptin)-5,5,6,6-d4 Stable Isotopes CS-O-46037 2892260-32-9 (Unlabelled) In Stock
Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 Stable Isotopes CS-O-46036 2892260-32-9 (Unlabelled) Enquire
N-Nitroso Sitagliptin Fumarate Adduct D4 Stable Isotopes CS-O-44423 Not Available Enquire
Rac-Sitagliptin-d4 xHCl Stable Isotopes CS-O-48530 1620233-77-3 Enquire
Sitagliptin D6 Stable Isotopes CS-O-39565 1133211-99-0 Enquire
Sitagliptin Fumarate Adduct D4 Stable Isotopes CS-O-54332 2088771-60-0(Unlabelled) Enquire
Sitagliptin Impurity 20-d4 HCl Stable Isotopes CS-P-09065 1620233-74-0 Enquire
Sitagliptin Triazecine Analog-D4 Stable Isotopes CS-T-96097 Not Available Enquire
Sitagliptin-d4 Hydrochloride Stable Isotopes CS-O-02775 1426173-93-4 (freebase) In Stock
Sitagliptin-d4 phosphate Stable Isotopes CS-O-06975 1432063-88-1 In Stock
Sitagliptin-D5 Stable Isotopes CS-O-47213 1133211-98-9 Enquire
rac-Sitagliptin-d4 Stable Isotopes CS-O-34315 823817-56-7 (Unlabeled) Enquire
Sitagliptin D4 Stable Isotopes CS-P-00279 486460-32-6 (Unlabeled) Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Sitagliptin API CS-O-31560 486460-32-6 In Stock
Sitagliptin Fumarate API CS-EO-03857 837430-24-7 Enquire
Sitagliptin Hydrochloride API CS-O-03409 486459-71-6 In Stock
Sitagliptin Hydrochloride Monohydrate API CS-O-35521 862156-92-1 In Stock
Sitagliptin Malate API CS-O-49400 1240039-02-4 Enquire
Sitagliptin Phosphate API CS-O-02325 654671-78-0 In Stock
rac-Sitagliptin API CS-T-61321 823817-56-7 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Sitagliptin-N-sulfate Metabolite CS-P-00283 940002-57-3 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(Butyl 4-hydroxy-3,5-bis(3-(trifluoromethyl)-5,6-dihydro-[1,... Impurity CS-O-45123 Not Available Enquire
(EZ)-Sitagliptin Styrylacetyl Analogue Impurity CS-T-73299 1675201-14-5 In Stock
(R)-Sitagliptin Methyl Ester Tartaric Acid Impurity Impurity CS-O-53710 1384431-02-0 Enquire
(R)-Sitagliptin Methyl-Ester Hydrochloride Impurity CS-EO-01677 1374985-05-3 Enquire
(R)-Sitagliptin Methyl-Ester Impurity Impurity CS-P-00280 881995-69-3 In Stock
(R)-Sitagliptin N-Boc-Methyl-Ester Impurity Impurity CS-EO-00173 881995-73-9 In Stock
(S)-Sitagliptin Hydrochloride Hydrate Impurity CS-O-46297 823817-55-6 (Freebase) Enquire
(S)-Sitagliptin Phosphate Monohydrate Impurity CS-O-53076 823817-55-6(Freebase) Enquire
2,3,5-trifluorophenyl (S)-Sitagliptin Impurity CS-O-45721 2507562-31-2 Enquire
2,3,5-trifluorophenyl Sitagliptin Impurity CS-O-44614 945261-49-4 Enquire
2,3,6-trifluorophenyl Sitagliptin Impurity CS-O-44613 945261-50-7 Enquire
2,5-Difluorophenylacetic acid Impurity CS-M-02541 85068-27-5 In Stock
2-chloro-N'-(2-chloroacetyl)acetohydrazide Impurity CS-ED-02498 89124-06-1 Enquire
2-Desfluoro sitagliptin Impurity CS-O-45482 486459-88-5 Enquire
3-(2,3,4-trifluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo... Impurity CS-O-52642 1159531-92-6 (Freebase) Enquire
3-(tert-butylamino) Sitagliptin Impurity CS-O-45502 Not Available Enquire
3,4-Difluorophenylacetic acid Impurity CS-M-02543 658-93-5 In Stock
3-Amino-4-(2,4,5-trifluorophenyl)butanyl Sitagliptin Impurity CS-T-66323 2072867-07-1 In Stock
4,10-Bis(4-bromobenzoyl)-6,11-dihydroindolo[3,2-c][1]benzaze... Impurity CS-O-54165 1644279-16-2 Enquire
4-[3-(3,5-Dichlorophenyl)-4,4,4-trifluoro-1-oxo-2-buten-1-yl... Impurity CS-O-54163 1422465-94-8 Enquire
4-Acetyl-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]et... Impurity CS-O-54164 1422465-93-7 Enquire
N-[(2Z)-Piperazin-2-ylidene]-2,2,2-trifluoroacetohydrazide Impurity CS-T-60617 849832-73-1 Enquire
N-Methyl Sitagliptin TFA Salt Impurity CS-O-53742 ---- Enquire
Oxo Sitagliptin Impurity CS-T-95811 Not Available Enquire
Rac- Sitagliptin Phosphate Impurity CS-O-14988 823817-57-8 In Stock
Rac-Sitagliptin Triazecine Analog Impurity CS-O-16935 2805078-75-3 In Stock
Sitagliptin acid Impurity CS-O-59284 936630-57-8 Enquire
Sitagliptin Acid impurity Impurity CS-P-00321 1204818-19-8 In Stock
Sitagliptin Acid Pivaloyl impurity Impurity CS-O-49103 1964462-19-8 Enquire
Sitagliptin Amide impurity Impurity CS-O-45501 2137101-64-3 Enquire
Sitagliptin Dimer Impurity Impurity CS-O-60359 ---- Enquire
Sitagliptin Dioxo SODIUM Impurity Impurity CS-O-42655 1253055-91-2 Enquire
Sitagliptin Enamine Impurity Impurity CS-EO-01488 767340-03-4 In Stock
Sitagliptin EP Impurity A Impurity CS-EO-00434 823817-55-6 In Stock
Sitagliptin EP Impurity A phosphate Impurity CS-O-08190 823817-58-9 In Stock
Sitagliptin EP Impurity B Impurity CS-O-08193 486460-31-5 In Stock
Sitagliptin EP Impurity C Impurity CS-O-08194 945261-48-3 In Stock
Sitagliptin EP Impurity E Impurity CS-O-08191 1283583-85-6 In Stock
Sitagliptin ethyl ester impurity Impurity CS-EO-02744 1151240-91-3 In Stock
Sitagliptin FP Impurity D Impurity CS-AQ-00108 1253056-18-6 In Stock
Sitagliptin Fumarate Adduct Impurity CS-O-16256 2088771-60-0 In Stock
Sitagliptin hydroxylimine impurity Impurity CS-O-47111 1253056-15-3 Enquire
Sitagliptin Impurity 116 Impurity CS-O-57678 2088771-62-2 Enquire
Sitagliptin Impurity 16 Impurity CS-O-58341 769195-20-2 Enquire
Sitagliptin Impurity 19 ((R)-Sitagliptin N-Boc-Acid Impurity... Impurity CS-O-31557 486460-00-8 Enquire
Sitagliptin Impurity 40 Impurity CS-EO-01196 1459759-18-2 Enquire
Sitagliptin Impurity 62 Impurity CS-P-09023 2379621-81-3 In Stock
Sitagliptin Impurity 81 Impurity CS-O-58080 667-35-6 Enquire
Sitagliptin Impurity 84 Impurity CS-EO-03216 2172431-08-0 Enquire
Sitagliptin Impurity 93 Impurity CS-O-49114 1246961-45-4 Enquire
Sitagliptin Impurity B Impurity CS-O-54616 2955636-26-5 Enquire
Sitagliptin impurity D Impurity CS-AQ-00099 767340-03-4 In Stock
Sitagliptin Impurity H Impurity CS-T-60052 764667-65-4 In Stock
Sitagliptin Intermediate Impurity CS-O-59479 ---- Enquire
Sitagliptin isopropyl ester impurity Impurity CS-O-45503 1802495-69-7 In Stock
Sitagliptin lactose impurity Impurity CS-O-57373 ---- Enquire
Sitagliptin N-Acetyl Impurity Impurity CS-O-08196 1379666-94-0 In Stock
Sitagliptin N-formyl impurity Impurity CS-O-34416 Not Available In Stock
Sitagliptin phosphate (Monohydrate) Impurity CS-O-02387 654671-77-9 In Stock
Sitagliptin Phosphate Hydrate Impurity CS-O-08197 654671-77-9 In Stock
Sitagliptin Propan-2-ylideneamino Impurity Impurity CS-O-60360 ---- Enquire
Sitagliptin Pyrazine Impurity Impurity CS-O-41913 486460-21-3 (Freebase) Enquire
Sitagliptin Styrylacetyl Analogue Impurity CS-O-15304 1803026-58-5 In Stock
Sitagliptin Triazecine Analog Impurity CS-P-08660 2088771-61-1 In Stock
Sitagliptin Triazecine Analog Dimer Impurity CS-O-59300 Not Available Enquire
(R)-tert-butyl (4-(1H-imidazol-1-yl)-4-oxo-1-(2,4,5-trifluor... Impurity CS-O-33867 1364122-90-6 Enquire
(S)-Sitagliptin acetate Impurity CS-O-41611 Not Available Enquire
(S)-Sitagliptin Hydrochloride Impurity CS-P-00287 823817-55-6 (Freebase) Enquire
1-(2,4,5-Trifluorophenyl)propan-2-amine Impurity CS-O-35820 910409-20-0 Enquire
4-Desfluoro Sitagliptin Impurity CS-TB-14828 1345822-87-8 Enquire
5-(Trifluoromethyl)-2-(chloromethyl)-1,3,4-oxadiazole Impurity CS-T-45317 723286-98-4 Enquire
Boc-(R)-3-Amino-4-phenylbutyric acid Impurity CS-DL-00775 101555-61-7 Enquire
Ethyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Impurity CS-T-77694 1151240-88-8 Enquire
Sitagliptin Amino Acid Impurity Impurity CS-O-41914 Not Available Enquire
Sitagliptin dioxo impurity Impurity CS-P-00288 Not Available Enquire
Sitagliptin EP Impurity C Phosphate Impurity CS-T-93839 1345822-86-7 Enquire
SITAGLIPTIN FORMIC ACID ADDUCT Impurity CS-O-40431 Not Available Enquire
Sitagliptin FP Impurity D (Z)-Isomer Impurity CS-O-40372 1803026-54-1 Enquire
Sitagliptin Impurity 28 Impurity CS-EO-01276 1283583-85-6 Enquire
Sitagliptin Impurity 39 Impurity CS-P-08948 1485732-85-1 Enquire
Sitagliptin Impurity 61 Impurity CS-EO-01819 1620129-74-9 Enquire
Sitagliptin impurity F Impurity CS-AQ-00098 1608491-98-0 Enquire
Sitagliptin impurity G Impurity CS-AQ-00101 54608-52-5 Enquire
Sitagliptin impurity H Hydrochloride Impurity CS-P-00284 1334244-24-4 (free base) Enquire
Sitagliptin impurity I Impurity CS-AQ-00102 Not Available Enquire
Sitagliptin impurity J Impurity CS-AQ-00103 Not Available Enquire
Sitagliptin impurity K Impurity CS-AQ-00104 Not Available Enquire
Sitagliptin impurity L Impurity CS-AQ-00105 851307-12-5 Enquire
Sitagliptin impurity N Impurity CS-P-00285 2409985-39-1 Enquire
Sitagliptin impurity R Impurity CS-AQ-00107 486459-98-7 Enquire
Sitagliptin impurity T Impurity CS-AQ-00109 Not Available Enquire
Sitagliptin impurity-4 Impurity CS-O-38621 1840966-95-1 Enquire
Sitagliptin tartrate hemihydrate Impurity CS-O-34792 Not Available Enquire
Sitagliptin+ Metformin Imp 4 Impurity CS-O-36495 Not Available Enquire


EP Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Sitagliptin phosphate monohydrate(Y0001812) EP Standards CS-EG-03289 654671-77-9 In Stock


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ethyl Trifluoroacetate Intermediate CS-T-23241 383-63-1 In Stock
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Intermediate CS-T-58393 769195-26-8 In Stock
N-Boc-Sitagliptin Intermediate CS-T-49555 486460-23-5 In Stock
Sitagliptin Triazole Hydrochloride Impurity Intermediate CS-O-08198 762240-92-6 In Stock
tert-butyl (1-(2,4,5-trifluorophenyl)propan-2-yl)carbamate Intermediate CS-O-49323 Not Available Enquire
(Z)-Methyl-3-amino-4-(2,4,5-trifluorophenyl)but-2-enoate Intermediate CS-O-44716 881995-70-6 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1-(4-MethylPhenyl)-4,4,4-trifluorobutane-1,3-dione Fine Chemicals CS-O-31308 720-94-5 In Stock
Glycolide Fine Chemicals CS-DE-01669 502-97-6 In Stock
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine Fine Chemicals CS-T-11134 762240-99-3 Enquire
3-oxo-4-(2,4,5-trifluorophenyl)butanoic acid Fine Chemicals CS-O-37598 1256815-03-8 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,4,5-Trifluorophenylacetic acid Building Blocks CS-M-01615 209995-38-0 In Stock
2,4,5-Trifluorobenzoyl chloride Building Blocks CS-M-01499 88419-56-1 Enquire
2,4,5-Trifluorophenylacetonitrile Building Blocks CS-M-01621 220141-74-2 Enquire