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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Pyrazine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Pyrazine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Pyrazine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Pyrazine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-N-(1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan... Stable Isotopes CS-T-97425 Not Available Enquire
(R)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyra... Stable Isotopes CS-T-97316 Not Available Enquire
2,3,5-Trimethylpyrazine-[d9] Stable Isotopes CS-I-00537 85735-49-5 Enquire
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a... Stable Isotopes CS-T-102007 Not Available Enquire
3,5-Dimethyl-2-ethyl-d5-pyrazine Stable Isotopes CS-T-100404 1082581-96-1 Enquire
3-Methyl-2,5-bis-(2-hydroxyethyl)pyrazine-d4 Stable Isotopes CS-T-101122 Not Available Enquire
5-Hydroxypyrazine-2-carboxylic Acid-13C3 Stable Isotopes CS-T-101269 Not Available Enquire
5-Hydroxypyrazinecarboxamide-13C3 Stable Isotopes CS-T-101268 Not Available Enquire
Coenzyme A S-Pyrazinecarboxylate-d3 Stable Isotopes CS-T-96987 Not Available Enquire
Hydroxy Tetramethylpyrazine-d11 Stable Isotopes CS-O-47469 Not Available Enquire
Sulfachloropyrazine-d4 Stable Isotopes CS-T-94444 102-65-8 Unlabelled Enquire
Sulfamethoxypyrazine-D4 Stable Isotopes CS-O-54342 ---- Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Sulfachloropyrazine sodium monohydrate API CS-O-15123 1392129-96-2 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid Impurity CS-T-93999 Not Available In Stock
(R)-N-(1-(3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyra... Impurity CS-O-48137 - Enquire
1,2,3,4-tetrahydropyrazine-Olaparib Keto Impurity Impurity CS-O-56601 ---- Enquire
2,5-Pyrazinedipropanoic Acid Impurity CS-T-96074 77479-02-8 Enquire
3-(2,3,4-trifluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo... Impurity CS-O-52642 1159531-92-6 (Freebase) Enquire
6-chloro-3-hydroxypyrazine-2-carboxamide Impurity CS-ZE-24720 259793-90-3 In Stock
Des(5-methylpyrazinecarbonyl) trans-4-Methyl Glipizide Impurity CS-T-89044 41176-98-1 In Stock
N-(1-((3-methyl-1-((3aS,4S,6S,7aS)-3a,5,5-trimethylhexahydro... Impurity CS-O-48138 - Enquire
Pipecuronium bromide tetrahydro pyrazine Impurity CS-O-52130 Not Available Enquire
Sitagliptin Pyrazine Impurity Impurity CS-O-41913 486460-21-3 (Freebase) Enquire
Sulfachloropyrazine Sodium Impurity CS-EO-03701 71720-40-6 In Stock
Sulfachlorpyrazine Impurity CS-O-48723 1672-91-9 Enquire
Vilagliptin Dioxo Pyrazine Impurity CS-O-44840 Not Available Enquire
Vildagliptin Pyrazine Dione impurity Impurity CS-EO-01542 1846606-32-3 Enquire
Vildagliptin Pyrazine impurity Impurity CS-O-56604 2797661-57-3 Enquire
(S)-N-(1-(3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyra... Impurity CS-O-14778 862894-96-0 Enquire
2-Amino-3,5-dibromopyrazine Impurity CS-T-65912 24241-18-7 Enquire
2-Amino-5-hydroxypyrazine Impurity CS-ZJ-14305 287916-14-7 Enquire
2-carbamoyl-6-fluoro-3-hydroxypyrazine 1-oxide Impurity CS-O-35780 Not Available Enquire
3,6-Difluoropyrazine-2-carboxamide Impurity CS-MM-45250 356783-29-4 Enquire
3-carbamoyl-5-fluoro-2-hydroxypyrazine 1,4-dioxide Impurity CS-O-35782 Not Available Enquire
3-carbamoyl-5-fluoro-2-hydroxypyrazine 1-oxide Impurity CS-O-35781 Not Available Enquire
5,6,7,8-Tetrahydro-3-phenyl-1,2,4-triazolo[4,3-a]pyrazine Impurity CS-T-61876 944906-91-6 Enquire
5-tosyl-5H-pyrrolo[2,3-b]pyrazine-2-carboxylic acid Impurity CS-O-36119 1201630-75-2 Enquire
6-fluoro-4-hydroxy-3-oxo-3,4-dihydropyrazine-2-carboxamide Impurity CS-O-35714 Not Available Enquire
6-Fluoro-pyrazine-2-carbonitrile Impurity CS-ZJ-18124 356783-46-5 Enquire
Ethyl 4-[-ß-(5-Methylpyrazine-2-carboxamido)ethyl]benzene Su... Impurity CS-T-23008 1076198-09-8 Enquire
methyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazine-2-carboxylate Impurity CS-O-36118 1201188-66-0 Enquire
N-(1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylprop... Impurity CS-O-38945 2747958-64-9 Enquire
N-Des(5-methylpyrazinecarbonyl)-N-ethylcarboxyl Glipizide Impurity CS-T-16428 13554-93-3 Enquire
Pyrazine-2-carboxylic acid (1-[3-methyl-1-(2,9-dimethyl-3,5-... Impurity CS-O-42129 Not Available Enquire
Pyrazine-2-carboxylic acid [1-(1-hydroxy-3-methyl-butyl carb... Impurity CS-O-36966 Not Available Enquire
Pyrazine-2-carboxylic acid(1-(3-methyl-butylcarbamoyl)-2-phe... Impurity CS-O-42127 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(E)-2-hydrazono-6-methoxy-1,2-dihydropyrazine Intermediate CS-O-49214 954227-93-1 Enquire
(E)-6-ethyl-2-hydrazono-1,2-dihydropyrazine Intermediate CS-O-49215 1551360-92-9 Enquire
5-hydroxypyrazine-2-carbonitrile Intermediate CS-O-54531 134510-05-7 Enquire
6-Chloropyrazine-2-carbonitrile Intermediate CS-T-72743 6863-74-7 In Stock
8-chloroimidazo[1,5-a]pyrazine Intermediate CS-O-49511 56468-23-6 Enquire
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarbo... Intermediate CS-T-03255 289472-80-6 In Stock
Pyrazinecarbonitrile Intermediate CS-M-57903 19847-12-2 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,3,5,6-Tetraphenylpyrazine Fine Chemicals CS-O-55449 642-04-6 Enquire
2,6-Dichloropyrazine Fine Chemicals CS-M-02559 4774-14-5 In Stock
3,6-Dichloropyrazine-2-carbonitrile Fine Chemicals CS-MM-44494 356783-16-9 Enquire
3,6-Difluoropyrazine-2-carbonitrile Fine Chemicals CS-MM-45249 356783-28-3 In Stock
5,6,7,8-Tetrahydroimidazo[1,2-a]Pyrazine Fine Chemicals CS-M-52957 91476-80-1 In Stock
6-Bromo-3-hydroxypyrazine-2-carboxamide Fine Chemicals CS-MM-50822 259793-88-9 In Stock
6-Methylpyrazine 2-Carboxylic Acid Fine Chemicals CS-O-01910 5521-61-9 In Stock
Pyrazine Fine Chemicals CS-M-00002 290-37-9 In Stock
pyrazine-2,5-diol Fine Chemicals CS-O-54528 134434-28-9 Enquire
Sulpha chloropyrazine sodium Fine Chemicals CS-K-00147 23307-72-4 In Stock
(2,4-difluorobenzyl)-9-ethoxy-2-[(1R)-3-hydroxy-1-methylprop... Fine Chemicals CS-O-38535 Not Available Enquire
2-Aminopyrazine Fine Chemicals CS-M-43097 5049-61-6 Enquire
2-Fluoro-6-iodo-pyrazine Fine Chemicals CS-MM-03888 1286744-13-5 Enquire
3,6-dihydroxypyrazine-2-carboxamide Fine Chemicals CS-O-36005 Not Available Enquire
3-Bromo-5H-pyrrolo[2,3-b]pyrazine Fine Chemicals CS-MM-43762 1260665-49-3 Enquire
3-methyl-6-phenylpyrazine-2-carboxylic acid Fine Chemicals CS-O-37954 1463442-68-3 Enquire
3-phenyl-2-(pyrazine-2-carboxamido)propanoic acid Fine Chemicals CS-O-37602 2364553-64-8 Enquire
6-Chloro-3,5-diamino-2-pyrazinecarboxamide Fine Chemicals CS-RS-00044 14236-57-8 Enquire
6-Fluoro-3-oxo-3,4-dihydropyrazine-2-carbonitrile Fine Chemicals CS-ZE-06349 356783-31-8 Enquire
Ethyl 5-chloropyrazine-2-carboxylate Fine Chemicals CS-ZE-36791 54013-04-6 Enquire
PYRAZINE-2,3-DIOL Fine Chemicals CS-ZE-24816 931-18-0 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-1-bromo-8-chloro-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5... Nitrosamine CS-O-60469 ---- Enquire
(S)-8-chloro-3-(1-nitrosopyrrolidin-2-yl)imidazo[1,5-a]pyraz... Nitrosamine CS-O-60470 ---- Enquire
1,10-dinitrosodecahydrodiimidazo[1,2-a:2',1'-c]pyrazine Nitrosamine CS-O-53752 ---- Enquire
7-Nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triaz... Nitrosamine CS-EO-01520-1.5ML 2892260-32-9 Enquire
Depyrazine 6,8-Dinitro-3-nitroso Varenicline Nitrosamine CS-O-44468 Not Available Enquire
N-nitroso Depyrazine 7,8-Dinitrophenyl Varenicline Nitrosamine CS-O-36135 2803960-63-4 In Stock


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2,3,5-Trimethylpyrazine-d10 Stable Isotope Reagent CS-C-01723 Not Available Enquire
2-bromopyrazine-3,5,6-d3 Stable Isotope Reagent CS-O-48830 1185316-30-6 Enquire
2-chloropyrazine-D3 Stable Isotope Reagent CS-O-49253 1374664-69-3 Enquire
3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a... Stable Isotope Reagent CS-C-02149 Not Available Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
1,​2,​3,​4-​tetrahydropyrazine Building Blocks CS-O-43317 5194-05-8 Enquire
2-(Trifluoromethyl)pyrazine Building Blocks CS-M-23570 61655-67-2 In Stock
3-Bromo-5-chloro-6-ethylpyrazine-2-carbonitrile Building Blocks CS-O-46896 2043020-03-5 Enquire
7-Methylpyrrolo[1,2-a]pyrazine-6,8-dithiol Building Blocks CS-O-56453 489395-81-5 Enquire
2-Cyano-5 methyl pyrazine Building Blocks CS-O-39787 98006-91-8 Enquire
2-ethyl-6-methylpyrazine Building Blocks CS-TA-44523 13925-03-6 Enquire
potassium 3-(dihydroxymethyl)pyrazine-2-carboxylate Building Blocks CS-O-35493 Not Available Enquire
tert-Butyl 3-bromo-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-c... Building Blocks CS-M-53046 949922-61-6 Enquire


Catalyst

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
5,6-Bis(5-methoxy-2-thienyl)-2,3-pyrazinedicarbonitrile Catalyst CS-O-57818 1818245-74-7 Enquire