Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Afatinib, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Afatinib impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Afatinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Our Afatinib-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.
Afatinib Related Compounds
Stable Isotopes
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (2Z)-Afatinib-d6 | Stable Isotopes | CS-T-97835 | Not Available | Enquire |
| Afatinib 13C6 | Stable Isotopes | CS-EK-02211 | 850140-72-6 unlabeled | Enquire |
| Afatinib D4 | Stable Isotopes | CS-O-13074 | 850140-72-6 ( Unlabeled) | Enquire |
| Afatinib-d6 | Stable Isotopes | CS-CX-00057 | 1313874-96-2 | In Stock |
| Afatinib-d6 Dimaleate | Stable Isotopes | CS-T-95339 | 1394292-94-4(Free base) | Enquire |
API Standards
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| Afatinib | API Standards | CS-T-01429 | 850140-72-6 | In Stock |
| Afatinib dimaleate | API Standards | CS-O-12080 | 850140-73-7 | In Stock |
Metabolites
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| 4-Hydroxy 4-Dedimethylamino Afatinib | Metabolites | CS-O-32669 | 2121530-37-6 | Enquire |
| Afatinib-N-Oxide | Metabolites | CS-O-10178 | Not Available | Enquire |
Impurities
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (2Z)-Afatinib | Impurities | CS-T-65303 | 1680184-59-1 | Enquire |
| (E)-4-(methylamino)but-2-enoic acid | Impurities | CS-O-60124 | 69169-63-7 | Enquire |
| Afatinib 5-hydroxypyrrolidin-2-one Impurity | Impurities | CS-EO-01168 | 2223677-58-3 | In Stock |
| Afatinib Bis-dimethylamino Impurity | Impurities | CS-O-56615 | 2414260-31-2 | Enquire |
| Afatinib Dimer impurity | Impurities | CS-O-47043 | 2223677-65-2 | Enquire |
| Afatinib Hydroxy impurity | Impurities | CS-O-47042 | 2223677-61-8 | Enquire |
| Afatinib Impurity 1 | Impurities | CS-O-13085 | Not Available | Enquire |
| Afatinib Impurity 10 | Impurities | CS-O-13094 | Not Available | Enquire |
| Afatinib Impurity 11 | Impurities | CS-O-57930 | 2413212-17-4 | Enquire |
| Afatinib Impurity 14 | Impurities | CS-O-57931 | 2413212-21-0 | Enquire |
| Afatinib Impurity 2 | Impurities | CS-O-13086 | 1449430-45-8 | Enquire |
| Afatinib Impurity 20 | Impurities | CS-EO-01428 | 1957132-02-3 | Enquire |
| Afatinib Impurity 23 | Impurities | CS-O-39578 | 2475095-50-0 | Enquire |
| Afatinib Impurity 27 | Impurities | CS-O-39522 | 618061-76-0 | Enquire |
| Afatinib Impurity 3 | Impurities | CS-O-13087 | Not Available | Enquire |
| Afatinib Impurity 4 | Impurities | CS-O-37644 | 2512206-82-3 | Enquire |
| Afatinib Impurity 4 | Impurities | CS-O-13088 | 2512206-82-3 | Enquire |
| Afatinib Impurity 5 | Impurities | CS-O-13089 | 179552-74-0 | In Stock |
| Afatinib Impurity 6 | Impurities | CS-O-13090 | Not Available | Enquire |
| Afatinib Impurity 7 | Impurities | CS-O-13091 | Not Available | Enquire |
| Afatinib Impurity 8 | Impurities | CS-O-13092 | Not Available | Enquire |
| Afatinib Impurity 9 | Impurities | CS-O-13093 | 2413212-10-7 | Enquire |
| Afatinib Impurity A | Impurities | CS-O-13075 | 402855-07-6 | Enquire |
| Afatinib Impurity AFT-8 | Impurities | CS-T-93669 | 2323570-72-3 | Enquire |
| Afatinib Impurity C | Impurities | CS-O-13077 | 945553-91-3 | Enquire |
| Afatinib Impurity D | Impurities | CS-O-13078 | 1680184-59-1 | Enquire |
| Afatinib Impurity E | Impurities | CS-O-13079 | 2223677-63-0 | Enquire |
| Afatinib Impurity F | Impurities | CS-O-13080 | 2223677-62-9 | Enquire |
| Afatinib Impurity G | Impurities | CS-O-13081 | Not Available | Enquire |
| Afatinib Impurity H | Impurities | CS-O-13082 | 2223677-64-1 | Enquire |
| Afatinib Impurity I | Impurities | CS-O-13083 | Not Available | Enquire |
| Afatinib Impurity J HCl | Impurities | CS-O-13084 | 1456696-14-2 (keto form) | Enquire |
| Afatinib imp-VI | Impurities | CS-O-34830 | 2223677-62-9 | In Stock |
| Afatinib Maleic Acid Adduct | Impurities | CS-P-08729 | Not Available | Enquire |
| Afatinib N-Oxide | Impurities | CS-EO-02865 | 2413212-11-8 | In Stock |
| Afatinib pyrrolidine-2,5-dione impurity | Impurities | CS-O-57964 | Not Available | Enquire |
| ethyl (E)-4-(dimethylamino)but-2-enoate hydrochloride | Impurities | CS-EO-01465 | 1255078-56-8 | Enquire |
Intermediates
| COMPOUND | CATEGORY | CAT. No. | CAS. No. | STOCK STATUS |
|---|---|---|---|---|
| (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)ox... | Intermediates | CS-O-13076 | 314771-76-1 | In Stock |
| Afatinib dichloro impurity | Intermediates | CS-ED-40634 | 2223677-63-0 | Enquire |
| trans-4-Dimethylaminocrotonic acid hydrochloride | Intermediates | CS-M-57341 | 848133-35-7 | In Stock |