Recently Viewed 0
Meet Clearsynth at CPHI Milan · October 6–8, 2026 · Booth 10F24 Book a meeting
My Account Need quick assistance? WhatsApp us +91-22-45045900 sales@clearsynth.com
Stable isotope-labeled compounds for analytical research
Stable isotope products

Stable Isotope-Labeled Compounds

Non-radioactive isotope-labelled materials for quantitative measurement, metabolism research, structural studies and synthetic chemistry.

Definition

What is a stable isotope-labeled compound?

It is a molecule in which selected atoms are enriched with non-radioactive isotopes such as deuterium (2H), carbon-13 (13C), nitrogen-15 (15N) or oxygen-18 (18O). The labelled molecule can be differentiated by mass or spectroscopy while retaining close chemical similarity to its unlabelled counterpart.

Isotope choice

The label must fit the method

Deuterium

Often provides an accessible mass shift. Position and hydrogen-deuterium exchange must be considered.

Carbon-13

A non-exchangeable label commonly used when close chromatographic behaviour and label stability are important.

Nitrogen-15

Useful in nitrogen-containing molecules, metabolic tracing and multi-isotope internal-standard designs.

Oxygen-18

Used in selected reaction, biochemical and tracer studies; incorporation and exchange conditions require review.

Multiple labels

Combined isotopes can increase mass separation or place a durable label at a structurally suitable site.

Unlabelled counterpart

The analyte structure, ion fragments, matrix, method and possible interference all influence the best standard.

Applications

Analytical and research uses

  • Internal standards for LC-MS/MS and GC-MS quantitation
  • Metabolic pathway, absorption and distribution research
  • Environmental and food residue analysis
  • Clinical, forensic and toxicology method development
  • Reaction-mechanism and isotope-tracing studies
  • Pharmaceutical impurity and metabolite research
Analytical instrumentation used for stable isotope materials
Done
RFQ Basket 0
Quick Enquiry
Tell us what you need
Quote Basket
Selected RFQ Items
Your RFQ basket is empty. Add a product block or copy a guided requirement here.