Trans-Abacavir Dihydrochloride
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仅供研究与分析用途。不可个人使用。
包装与处理
所示为供视觉参考的示意性产品包装。实际包装可能因包装规格、数量、储存条件和运输要求而异。
可提供文档
可应要求提供详细规格、证书和支持性文件。
可应要求提供详细规格、证书和支持性文件。
储存： 完整信息请参阅 MSDS。
危害： 准确信息请参阅 MSDS。
Trans-Abacavir Dihydrochloride 产品信息
Trans-Abacavir Dihydrochloride 归类于 Impurity，用于分析研究、质量控制和药物对照品应用。 其关联物质为 Abacavir. 本产品由 Clearsynth 提供，目录号为 CS-BI-00051.
Clearsynth 提供该化合物用于研究和分析用途，产品信息包括 CAS 号、分子式、分子量和产品咨询详情。
技术数据
描述
法规说明
Trans-Abacavir Dihydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Trans-Abacavir Dihydrochloride can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Abacavir.
概述
trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2?-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
同义词
Trans-Abacavir Dihydrochloride
应用说明
trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2?-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
产品应用与法规搜索词
此参考标准的有用产品、供应商和法规搜索词。