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Candesartan

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Candesartan

API · API 系列: Candesartan · CAT 编号 CS-O-01145 · CAS 编号 139481-59-7
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所示为供视觉参考的示意性产品包装。实际包装可能因包装规格、数量、储存条件和运输要求而异。

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可应要求提供详细规格、证书和支持性文件。
储存: 完整信息请参阅 MSDS。
危害: 准确信息请参阅 MSDS。

Candesartan 产品信息

Candesartan 归类于 API,用于分析研究、质量控制和药物对照品应用。 其关联物质为 Candesartan. 本产品由 Clearsynth 提供,目录号为 CS-O-01145.

Clearsynth 提供该化合物用于研究和分析用途,产品信息包括 CAS 号、分子式、分子量和产品咨询详情。

技术数据

产品名称
Candesartan
CAS 编号
139481-59-7
CAT 编号
CS-O-01145
HSN 代码
38229010
原产国
Can be shipped from India, Canada and USA
分子式
C24H20N6O3
分子量
440.45
类别
API 系列
储存条件
完整信息请参阅 MSDS。
危险化合物
准确信息请参阅 MSDS。

描述

法规说明
Candesartan is supplied with detailed characterization data compliant with regulatory guideline. Candesartan can be used for analytical method development, method validation (AMV), Quality Control (QC) application for Abbreviated New Drug Application (ANDA), or during commercial production of Candesartan.
概述
"Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease."
同义词
Candesartan
应用说明
"Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease."
参考文献

产品应用与法规搜索词

此参考标准的有用产品、供应商和法规搜索词。

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