AZD6738-d4
实时
已添加到 RFQ
仅供研究与分析用途。不可个人使用。
包装与处理
所示为供视觉参考的示意性产品包装。实际包装可能因包装规格、数量、储存条件和运输要求而异。
可提供文档
可应要求提供详细规格、证书和支持性文件。
可应要求提供详细规格、证书和支持性文件。
储存： 完整信息请参阅 MSDS。
危害： 完整信息请参阅 MSDS。
AZD6738-d4 产品信息
AZD6738-d4 归类于 Stable Isotopes，用于分析研究、质量控制和药物对照品应用。 本产品由 Clearsynth 提供，目录号为 CS-T-103295.
Clearsynth 提供该化合物用于研究和分析用途，产品信息包括 CAS 号、分子式、分子量和产品咨询详情。
技术数据
产品名称
AZD6738-d4
CAT 编号
CS-T-103295
HSN 代码
38229010
原产国
Can be shipped from India, Canada and USA
分子式
C20H20D4N6O2S
分子量
416.53
储存条件
完整信息请参阅 MSDS。
危险化合物
完整信息请参阅 MSDS。
描述
法规说明
AZD6738-d4 is supplied with detailed characterization data compliant with regulatory guideline. AZD6738-d4 can be used for analytical method development, method validation (AMV), Quality Control (QC), ANDA-related analytical work, and commercial pharmaceutical research applications.
概述
AZD6738-d4, is a labeled analogue of AZD6738 (A965423), an orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase, with potential antineoplastic activity. Upon oral administration, ATR kinase inhibitor AZD6738 selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis. In addition, AZD6738 sensitizes tumor cells to chemo- and radiotherapy. ATR, a serine/threonine protein kinase upregulated in a variety of cancer cell types, plays a key role in DNA repair, cell cycle progression, and survival; it i
同义词
AZD6738-d4
应用说明
AZD6738-d4, is a labeled analogue of AZD6738 (A965423), an orally available morpholino-pyrimidine-based inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase, with potential antineoplastic activity. Upon oral administration, ATR kinase inhibitor AZD6738 selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated signaling, and results in the inhibition of DNA damage checkpoint activation, disruption of DNA damage repair, and the induction of tumor cell apoptosis. In addition, AZD6738 sensitizes tumor cells to chemo- and radiotherapy. ATR, a serine/threonine protein kinase upregulated in a variety of cancer cell types, plays a key role in DNA repair, cell cycle progression, and survival; it i
产品应用与法规搜索词
此参考标准的有用产品、供应商和法规搜索词。