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主页 Stable Isotopes CS-T-102235

5-Fluoroorotic Acid Monohydrate-13C15N2

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5-Fluoroorotic Acid Monohydrate-13C15N2

Stable Isotopes · CAT 编号 CS-T-102235
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仅供研究与分析用途。不可个人使用。
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所示为供视觉参考的示意性产品包装。实际包装可能因包装规格、数量、储存条件和运输要求而异。

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储存: 完整信息请参阅 MSDS。
危害: 完整信息请参阅 MSDS。

5-Fluoroorotic Acid Monohydrate-13C15N2 产品信息

5-Fluoroorotic Acid Monohydrate-13C15N2 归类于 Stable Isotopes,用于分析研究、质量控制和药物对照品应用。 本产品由 Clearsynth 提供,目录号为 CS-T-102235.

Clearsynth 提供该化合物用于研究和分析用途,产品信息包括 CAS 号、分子式、分子量和产品咨询详情。

技术数据

产品名称
5-Fluoroorotic Acid Monohydrate-13C15N2
CAT 编号
CS-T-102235
HSN 代码
38229010
原产国
Can be shipped from India, Canada and USA
分子式
C413CH5F15N2O5
分子量
195.08
储存条件
完整信息请参阅 MSDS。
危险化合物
完整信息请参阅 MSDS。

描述

法规说明
5-Fluoroorotic Acid Monohydrate-13C15N2 is supplied with detailed characterization data compliant with regulatory guideline. 5-Fluoroorotic Acid Monohydrate-13C15N2 can be used for analytical method development, method validation (AMV), Quality Control (QC), ANDA-related analytical work, and commercial pharmaceutical research applications.
概述
"5-Fluoroorotic Acid Monohydrate-13C15N2 is the isotope analog of 5-Fluoroorotic Acid Monohydrate, (5-FOA). 5-FOA has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroqu"
同义词
5-Fluoroorotic Acid Monohydrate-13C15N2
应用说明
"5-Fluoroorotic Acid Monohydrate-13C15N2 is the isotope analog of 5-Fluoroorotic Acid Monohydrate, (5-FOA). 5-FOA has become a valuable tool for research in the field of molecular genetics. It has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5'-phosphate decarboxylase deficient. 5-FOA is coverted to 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into RNA or metabolized to the highly toxic 5-fluoro-2’-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a potent inhibitor of thymidylate synthase (TS), causing the cessation of DNA synthesis. More recently, 5-FOA has been shown to possess potent antimalarial activity against both chloroquine-susceptible and chloroqu"
参考文献

产品应用与法规搜索词

此参考标准的有用产品、供应商和法规搜索词。

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