Nelarabine is a chemotherapy drug used to treat T-cell acute lymphoblastic leukemia. Nelarabine impurities are unwanted substances that may be present in the drug substance, which can affect the drug's safety and efficacy. These impurities are monitored closely during the drug's manufacturing process to ensure that the drug is of high quality and free from harmful contaminants. The identification and control of Nelarabine impurities are critical for the drug's safe and effective use in cancer treatment.