3(s), 5(s)-Dihydroxy Simvastatin-d3

Product Name 3(s), 5(s)-Dihydroxy Simvastatin-d3
Alternate Names Simvastatin Stable Isotopes, Stable Isotopes of Simvastatin
CAT No. CS-BV-00005
CAS No. 159143-77-8 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Simvastatin
Therapeutic Anti-Diabetic
Smileys C[C@@H]1[C@@H]([C@]([C@H](C[C@H]2C)OC(C(C)(C([2H])([2H])[2H])CC)=O)([H])C([C@H]2O)=C[C@H]1O)CC[C@@H](OC3=O)C[C@H](C3)O
Canonical Smiles CCC(C)(C)C(=O)OC1CC(C(C2=CC(C(C(C12)CCC3CC(CC(=O)O3)O)C)O)O)C
InchIKey MRCKOKWQDZYFLT-GBCWWPGNSA-N
Inchl InChI=1S/C25H40O7/c1-6-25(4,5)24(30)32-20-9-13(2)23(29)18-12-19(27)14(3)17(22(18)20)8-7-16-10-15(26)11-21(28)31-16/h12-17,19-20,22-23,26-27,29H,6-11H2,1-5H3/t13-,14-,15-,16?,17+,19?,20+,22-,23?/m1/s1
IUPAC [(1S,3R,7R,8S,8aR)-4,6-dihydroxy-8-[2-[(4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,4,6,7,8,8a-octahydronaphthalen-1-yl] 2,2-dimethylbutanoate
Controlled No
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3(s), 5(s)-Dihydroxy Simvastatin-d3 is a deuterated form of Simvastatin, which is a well-known medication used for treating high cholesterol and reducing the risk of heart disease. Simvastatin is classified as a statin drug that works by inhibiting the enzyme HMG-CoA reductase, which is responsible for producing cholesterol in the liver. By blocking this enzyme, Simvastatin reduces the amount of cholesterol in the bloodstream, which helps to prevent the buildup of plaque in the arteries and lowers the risk of heart attacks and strokes. 3(s), 5(s)-Dihydroxy Simvastatin-d3 is a labeled form of Simvastatin that contains deuterium atoms instead of hydrogen atoms. The deuterium atoms do not significantly alter the chemical properties of the drug, but they allow researchers to track the drug's metabolic pathway and measure its pharmacokinetics in vivo. This makes 3(s), 5(s)-Dihydroxy Simvastatin-d3 a valuable tool for studying the metabolism and pharmacology of Simvastatin in preclinical and clinical settings. In summary, 3(s), 5(s)-Dihydroxy Simvastatin-d3 is a deuterated form of Simvastatin that is used for research purposes to study the metabolism and pharmacokinetics of the drug. Simvastatin is a medication used for treating high cholesterol and reducing the risk of heart disease by inhibiting the production of cholesterol in the liver.

Related Compounds

Simvastatin D6 Lactone | Simvastatin Acid D6 | Simvastatin hydroxyl acid D6 Sodium salt | Simvastatin D3 | Simvastatin 13C D3 | Simvastatin D3 Lactone | Simvastatin acid D3 | Simvastatin hydroxy acid D3 ammonium salt | Simvastatin hydroxy acid D6 ammonium salt | Simvastatin-D6 sodium salt |

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