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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Lactone, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Lactone impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Lactone-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Lactone Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(R/S)-δ-Hexalactone-d6 Stable Isotopes CS-T-102943 823-22-3(Unlabelled) Enquire
4-Dehydroxy-3-dehydro-pitavastatin-d5 Lactone Stable Isotopes CS-T-97649 Not Available Enquire
6-Phosphoglucono-δ-lactone-13C6 Stable Isotopes CS-T-94319 2641-81-8(unlabelled) Enquire
6β-Hydroxy-7α-thiomethylspironolactone-d3 Stable Isotopes CS-O-56566 42219-60-3 (Unlabelled) Enquire
7-Alpha-Thiomethyl Spironolactone-d3 Stable Isotopes CS-O-03646 38753-77-4(Unlabeled) In Stock
7a-Thiomethyl Spironolactone-d7 (Major) Stable Isotopes CS-T-102348 38753-77-4 (Unlabelled) Enquire
Amitifadine Lactone-d5 Stable Isotopes CS-T-100839 2714485-10-4 Enquire
Atorvastatin-d5 (N-(phenyl-d5) Lactone Stable Isotopes CS-TA-20572 265989-48-8 Enquire
D-[1-13C]glucono-1,5-lactone Stable Isotopes CS-OC-00589 90-80-2 (unlabeled) Enquire
D-[6,6'-D2]glucono-1,5-lactone Stable Isotopes CS-OC-00643 90-80-2 (unlabeled) Enquire
D-[6-13C]glucono-1,5-lactone Stable Isotopes CS-OC-00574 90-80-2 (unlabeled) Enquire
D-[UL-13C6]glucono-1,5-lactone Stable Isotopes CS-OC-00571 90-80-2 (unlabeled) Enquire
D-[UL-13C6]glucurono-6,3-lactone Stable Isotopes CS-OC-00196 32449-92-6 (unlabeled) Enquire
gamma-Butyrolactone-[D6] Stable Isotopes CS-I-00647 77568-65-1 Enquire
Geissman Lactone-d2 Stable Isotopes CS-T-100271 Not Available Enquire
L-[UL-13C6]gulono-1,4-lactone Stable Isotopes CS-OC-00470 1128-23-0 (unlabeled) Enquire
N-Desmethyl Rosuvastatin Lactone-d6 Stable Isotopes CS-T-97619 Not Available Enquire
Pitavastatin Lactone-d4 Stable Isotopes CS-O-13751 141750-63-2(Unlabeled) In Stock
Pravastatin Lactone Di-(tert-butyldimethylsilyl) Ether-d3 Stable Isotopes CS-T-97206 Not Available Enquire
Pravastatin-D9 Lactone Di-(tert-butyldimethylsilyl) Ether Stable Isotopes CS-T-97207 Not Available Enquire
Pravastatin-d9 δ-Valerolactone Stable Isotopes CS-T-97208 Not Available Enquire
Simvastatin-d3 Lactone Stable Isotopes CS-O-02676 1002347-61-6 In Stock
Spironolactone-d3 Stable Isotopes CS-O-00897 52-01-7 (Unlabeled) In Stock
Spironolactone-d7 (Major) Stable Isotopes CS-O-15143 52-01-7(Unlabeled) In Stock
γ-Valerolactone-d3 Stable Isotopes CS-T-103808 108-29-2(unlabelled) Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Brachialactone API CS-O-57842 ---- Enquire
D-Erythronolactone API CS-T-54187 15667-21-7 Enquire
Galanolactone API CS-E-00773 115753-79-2 Enquire
Spironolactone API CS-O-30758 52-01-7 In Stock
Testolactone API CS-O-48236 968-93-4 Enquire
Testololactone API CS-T-61662 4416-57-3 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-Hydroxy Atorvastatin Lactone Metabolite CS-O-14406 163217-74-1 In Stock
4-Hydroxy Atorvastatin Lactone Metabolite CS-O-07274 163217-70-7 In Stock
7-Alpha-Thiomethyl Spironolactone Metabolite CS-O-30463 38753-77-4 In Stock
Desacetylcefotaxime Lactone Metabolite CS-O-05961 66340-33-8 In Stock
Pitavastatin Lactone Metabolite CS-O-05982 141750-63-2 In Stock
Quinic acid lactone Metabolite CS-Y-00141 665-27-0 Enquire
Simalikalactone D Metabolite CS-ED-41633 35321-80-3 Enquire
Simvastatin Lactone Metabolite CS-O-05972 79902-63-9 In Stock


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(+)-Corey Lactone Benzoate Impurity CS-T-91533 53275-53-9 Enquire
(+)-Hydroxycitric acid lactone Impurity CS-E-00927 27750-13-6 Enquire
(3R,5R)-Rosuvastatin Lactone Impurity CS-T-85371 1422954-11-7 Enquire
1,2-O-Isopropylidene-α-D-glucofuranosidurono-6,3-lacton... Impurity CS-T-56871 20513-98-8 Enquire
1,2-O-Isopropylidene-β-L-idofuranurono-6,3-lactone Impurity CS-T-56863 29514-28-1 Enquire
2,3,4,6-Tetra-O-(trimethylsilyl)-D-glucono-1,5-lactone Impurity CS-O-32367 32384-65-9 In Stock
2,3,4,6-Tetra-O-benzyl-D-glucono-1,5-lactone Impurity CS-T-61735 13096-62-3 Enquire
3,5-dihydroxy-2-deoxy-2-chloro-2-C-methyl-D-ribono-γ-lactone Impurity CS-N-05198 1496551-64-4 Enquire
3,5-di-O-benzoyl-2-deoxy-2-chloro-2-C-methyl-D-ribono-γ-lact... Impurity CS-N-05197 1496551-65-5 Enquire
6-epi Pravastatin Lactone Impurity CS-T-60712 85956-23-6 Enquire
6-β-Hydroxy-7-α-thiomethyl Spironolactone Impurity CS-T-56504 42219-60-3 Enquire
Anhydro Lovastatin Lactone Impurity CS-O-05512 109273-98-5 In Stock
Atorvastatin Dehydro Lactone Impurity CS-P-07050 442851-50-5 In Stock
Atorvastatin Lactone Diepoxide Impurity CS-O-14628 1046118-40-4 In Stock
Atorvastatin Pyrrolidone Lactone Impurity CS-P-03231 906552-19-0 In Stock
Betamethasone 20-keto-22,17-lactone Impurity CS-O-52526 Not Available Enquire
Calcitriol Lactone Impurity CS-T-69563 81203-50-1 Enquire
Caprolactone polymer Impurity CS-O-33877 24980-41-4 In Stock
Cefdinir Lactone Impurity CS-T-50421 946573-41-7 In Stock
Cefotetan Lactone Impurity CS-T-96083 Not Available Enquire
cis-trans Nepetalactone Impurity CS-T-59229 21651-62-7 Enquire
Corey lactone-4-(tert-Butyldimethylsilyl)oxy)-5-(tetrahydro-... Impurity CS-O-57331 65025-95-8 Enquire
Dapagliflozin Bromo lactone impurity Impurity CS-O-34035 ---- In Stock
Daptomycin Lactone hydrolysis Impurity CS-O-35562 Not Available Enquire
Decarbamylcefoxitin Lactone Impurity CS-T-73463 1422023-33-3 Enquire
Dehydro Ascorbic Acid (threo-2,3-Hexodiulosonic Acid, gama-l... Impurity CS-P-07068 33124-69-5 Enquire
delta-Valerolactone Impurity CS-T-46227 542-28-9 In Stock
D-Glucaric acid 1,4:6,3-dilactone Impurity CS-O-35230 826-91-5 Enquire
DL-Homocysteine Thiolactone Impurity CS-P-07516 10593-85-8 Enquire
D-Ribonolactone Impurity CS-T-61142 5336-08-3 Enquire
E-Cefdinir Lactone Impurity CS-O-56651 ---- Enquire
ent-Rosuvastatin Lactone Impurity CS-T-41967 615263-62-2 Enquire
Fluvastatin Lactone Sodium Impurity CS-O-39886 94061-83-3 (freebase) Enquire
Irinotecan Lactone chloride salt Impurity CS-EO-03623 143490-53-3 (Freebase) Enquire
Irinotecan Lactone Impurity Impurity CS-T-56775 143490-53-3 Enquire
Latanoprost-1,9-lactone Impurity CS-O-41413 1261926-71-9 Enquire
LCH gamma lactone Impurity CS-O-16670 Not Available Enquire
L-Erythrono-1,4-lactone Impurity CS-T-54179 23732-40-3 Enquire
Lovastatin Lactone Diol Impurity CS-O-08186 79952-42-4 In Stock
L-Ribono-1,4-lactone Impurity CS-T-61141 133908-85-7 Enquire
Mycophenolic Acid Lactone (EP Impurity H) Impurity CS-T-83349 79081-87-1 In Stock
Mycophenolic Lactone Ether Impurity CS-O-51993 26693-54-9 In Stock
O(phenyl)-Triisopropylsilyl Jasplakinolide seco-Lactone Meth... Impurity CS-ED-26818 943858-37-5 Enquire
Prasugrel Hydroxy Thiolactone Impurity CS-T-60709 947502-66-1 In Stock
Pravastatin Lactone Impurity CS-O-30741 85956-22-5 Enquire
Rosuvastatin Anhydro Lactone Impurity CS-T-41964 1246665-85-9 In Stock
Ruxolitinib Lactone Impurity Impurity CS-EO-01330 Not Available Enquire
Spironolactone EP impurity B Impurity CS-O-10704 Not Available Enquire
Spironolactone EP Impurity D Impurity CS-O-10706 3079028-52-4 In Stock
Spironolactone EP Impurity H Impurity CS-O-10710 53866-24-3 In Stock
Tolterodine Lactone Impurity Impurity CS-T-34918 40546-94-9 In Stock


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Cyclic 2,3-O-oxalyl L-threonolactone Intermediate CS-O-54873 ---- Enquire
L-Glucono-1,5-lactone Intermediate CS-O-10972 52153-09-0 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(rac-Enterolactone)-O-glucuronide (Mixture of Diastereomers) Glucuronide CS-T-92383 768385-57-5 Enquire
2,3,4,6-Tetra-O-benzyl-5-thio-D-glucono-1,5-lactone Glucuronide CS-O-51172 131757-92-1 Enquire
D-(+)-Glucuronic Acid-Lactone Glucuronide CS-O-10824 32449-92-6 In Stock
D-glucaro-1,4-lactone Glucuronide CS-ED-00787 389-36-6 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
4-Hydroxybutanoic acid lactone Fine Chemicals CS-O-13298 96-48-0 In Stock
b-Propiolactone Fine Chemicals CS-T-40660 57-57-8 In Stock
D-Galactonolactone Fine Chemicals CS-ED-01884 15892-28-1 Enquire
Gamma-Decalactone Fine Chemicals CS-E-00220 706-14-9 In Stock
Glucuronolactone Fine Chemicals CS-O-01595 32499-92-6 In Stock
Lachnophyllum Lactone Fine Chemicals CS-O-57812 23251-68-5 Enquire
L-Glucurono-3,6-lactone Fine Chemicals CS-T-55361 32449-80-2 Enquire
ε-​Caprolactone Fine Chemicals CS-T-70916 502-44-3 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
D-Glucono-1,4-Lactone Building Blocks CS-EP-00191 1198-69-2 Enquire
Yoshimulactone Green (YLG) Building Blocks CS-DE-01658 1807549-00-3 Enquire


Carbohydrates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
D-Galactono-1,4-lactone Carbohydrates CS-T-55192 2782-07-2 Enquire
L-Galactono-1,4-lactone Carbohydrates CS-T-55193 1668-08-2 Enquire
L-lyxono-1,4-lactone Carbohydrates CS-OC-00117 104196-15-8 Enquire


Chiral

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
D-(+)-Glucono-1,5-lactone Chiral CS-T-25298 90-80-2 In Stock


Deuterated Reagents

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
γ-Butyrolactone-d6 Deuterated Reagents CS-T-62871 77568-65-1 Enquire


Stable Isotope Reagent

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(±)-d-Hexalactone (5,5,6-d3, methyl-d3) Stable Isotope Reagent CS-C-02155 2124294-74-0 Enquire
(±)-Mevalonolactone-4,4,5,5,6,6,6-d7 Stable Isotope Reagent CS-C-02134 347840-19-1 Enquire
DL-Homocysteine Thiolactone-3,3,4,4-d4 Stable Isotope Reagent CS-C-01999 1219805-31-8 Enquire
epsilon-Caprolactone-3,3,4,4,5,5-d6 Stable Isotope Reagent CS-C-01732 1219802-08-0 Enquire
Gamma - Decalactone - d7 Stable Isotope Reagent CS-O-53080 1104979-33-0 Enquire
gamma-Dodecalactone d2 Stable Isotope Reagent CS-O-53084 1082581-85-8 Enquire


Therapeutic

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(-) Corey Lactone Therapeutic CS-T-13328 32233-40-2 In Stock
Atorvastatin Lactone Therapeutic CS-O-07292 125995-03-1 In Stock
Cefdinir Decarboxy Open Ring Lactone (Mixture of A and B) Therapeutic CS-O-10171 178949-04-7 Enquire
Rosuvastatin Lactone d6 Therapeutic CS-P-06214 503610-43-3(Unlabeled) In Stock
Spironolactone EP impurity A Therapeutic CS-O-10703 132458-33-4 Enquire
Spironolactone EP Impurity C Therapeutic CS-O-10705 976-70-5 In Stock
Spironolactone EP Impurity E Therapeutic CS-O-10707 33784-05-3 In Stock
Spironolactone EP impurity G Therapeutic CS-O-10709 880106-10-5 In Stock
Spironolactone EP Impurity I Therapeutic CS-O-10711 3070439-36-7 In Stock
Tacrolimus Lactone Isomer Therapeutic CS-O-08222 134590-88-8 Enquire