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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Ivabradine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Ivabradine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Ivabradine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Ivabradine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Dehydro Ivabradine-d3 Stable Isotopes CS-T-73566 1795787-01-7 Enquire
Ivabradine-d3 Stable Isotopes CS-O-03179 1217977-70-2 In Stock
Ivabradine-D3 Hydrochloride Stable Isotopes CS-O-15064 1217809-61-4 Enquire
Ivabradine-d4 Hydrochloride Stable Isotopes CS-T-93261 Not Available Enquire
Ivabradine-d6 Hydrochloride Stable Isotopes CS-O-06695 148870-59-1(Unlabeled) In Stock
N-Desmethyl Ivabradine D4 Hydrochloride Stable Isotopes CS-T-93262 Not Available Enquire
N-Desmethyl Ivabradine-d6 Hydrochloride Stable Isotopes CS-O-06693 1346600-74-5 In Stock
N-Desmethyl-Ivabradine D6 Stable Isotopes CS-O-14399 1346746-80-2 Enquire
Rac-Ivabradine D6 Stable Isotopes CS-EO-02954 148870-59-1 (Unlabeled free base) Enquire


API Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Ivabradine API Standards CS-O-01679 155974-00-8 In Stock
Ivabradine HCl racemic mixture API Standards CS-O-41636 Not Available Enquire
Ivabradine Hydrochloride API Standards CS-O-11672 148849-67-6 In Stock


Metabolites

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-hydroxy R-Ivabradine impurity Metabolites CS-O-45746 Not Available Enquire
Ivabradine N-Oxide Impurity Metabolites CS-O-10356 2511244-97-4 In Stock
N-Desmethyl Ivabradine Metabolites CS-O-06005 215935-23-2 Enquire


Impurities

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-m... Impurities CS-EO-02011 866783-12-2 Enquire
(S)-3-(3-((3-chloro-2-(3,4-dimethoxyphenyl)propyl)(methyl)am... Impurities CS-O-35681 Not Available Enquire
1-Hydroxy Ivabradine Impurities CS-K-00308 2511244-96-3 Enquire
2-Oxo-Ivabradine Impurities CS-O-52416 1616710-52-1 Enquire
3-(3-{[((7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7- ... Impurities CS-O-35969 2253977-80-7 Enquire
3-Hydroxy Ivabradine Hydrochloride Impurities CS-EO-03632 304464-98-0 (Freebase) Enquire
7,8-Dimethoxy-3-propyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-... Impurities CS-O-49110 2512208-76-1 Enquire
7-Demethyl Ivabradine (HCl salt) Impurities CS-EO-03630 304462-60-0 (Freebase) Enquire
8-Demethyl Ivabradine (HCl salt) Impurities CS-EO-03631 304464-97-9 (Freebase) Enquire
Dehydro Ivabradine HCl salt Impurities CS-O-34415 1086026-38-1 Enquire
Dehydro Ivabradine Oxalate Impurities CS-P-01058 1346558-08-4 Enquire
Demethyl Ivabradine HCl Impurities CS-O-35711 304465-03-0 (free base) Enquire
Ivabradine 12 Isomer Impurity Impurities CS-EO-02858 Not Available Enquire
Ivabradine 3-chloro N-methylpropanamine-Benzocyclobutane imp... Impurities CS-O-45771 1031767-71-1 In Stock
Ivabradine Acetyl analogue Impurities CS-EO-00280 2512206-14-1 Enquire
Ivabradine Amine Hydrochloride Impurities CS-O-32291 866783-13-3 In Stock
Ivabradine Dimer Impurities CS-O-16956 Not Available Enquire
Ivabradine Hydroxy Intemrediate Impurities CS-P-01059 1235547-07-5 Enquire
Ivabradine Impurity 1 Impurities CS-P-01060 1462470-54-7 Enquire
Ivabradine Impurity 10 Impurities CS-P-01069 Not Available Enquire
Ivabradine Impurity 11 Impurities CS-P-01070 1132667-04-9 Enquire
Ivabradine Impurity 12 Impurities CS-P-01071 85175-52-6 (Salt form) Enquire
Ivabradine Impurity 13 Impurities CS-P-01072 Not Available Enquire
Ivabradine Impurity 14 Impurities CS-P-01073 Not Available Enquire
Ivabradine Impurity 15 Impurities CS-P-01074 1616710-50-9 Enquire
Ivabradine Impurity 16 Impurities CS-P-01075 304464-98-0 Enquire
Ivabradine Impurity 2 Impurities CS-P-01061 73954-34-4 In Stock
Ivabradine Impurity 20 Impurities CS-O-59358 Not Available Enquire
Ivabradine Impurity 24 Impurities CS-O-59339 Not Available Enquire
Ivabradine Impurity 25 Impurities CS-EO-01002 1797099-93-4 Enquire
Ivabradine Impurity 26 Impurities CS-EO-01001 Not Available Enquire
Ivabradine Impurity 27 HCl Impurities CS-O-56491 2768438-46-4 (Freebase) Enquire
Ivabradine Impurity 28 HCl Impurities CS-O-56493 Not Available Enquire
Ivabradine Impurity 3 Impurities CS-P-01062 Not Available Enquire
Ivabradine Impurity 32 HCl Impurities CS-O-56495 Not Available Enquire
Ivabradine Impurity 33 HCl Impurities CS-O-56458 96254-66-9 (free base) Enquire
Ivabradine Impurity 34 HCl Impurities CS-O-56459 2373259-08-4 (free base) Enquire
Ivabradine Impurity 37 Impurities CS-EO-01061 Not Available Enquire
Ivabradine Impurity 4 Impurities CS-P-01063 Not Available Enquire
Ivabradine Impurity 44 Impurities CS-O-58502 1616710-51-0 Enquire
Ivabradine Impurity 5 Impurities CS-P-01064 Not Available Enquire
Ivabradine Impurity 6 Impurities CS-P-01065 869856-07-5 Enquire
Ivabradine Impurity 6 HCl Impurities CS-P-08786 Not Available Enquire
Ivabradine Impurity 62 Impurities CS-O-59369 2458312-06-4 Enquire
Ivabradine Impurity 8 Impurities CS-P-01067 85175-65-1 Enquire
Ivabradine Impurity 9 Impurities CS-P-01068 Not Available Enquire
Ivabradine Impurity B Impurities CS-O-35441 Not Available Enquire
Ivabradine Nitroso Impurity 1 Impurities CS-EO-03201 Not Available Enquire
Ivabradine Open Ring Hydrochloride Impurities CS-O-48708 1462470-54-7 (Freebase) Enquire
Ivabradine oxalate Impurities CS-O-36919 1086026-42-7 Enquire
Ivabradine Oxalate Impurity B Impurities CS-O-36920 Not Available Enquire
N-desmethyl Ivabradine HCl Impurities CS-T-16433 1246638-08-3 In Stock
N-Nitroso N-Desmethyl Ivabradine Impurities CS-EO-01261 Not Available Enquire
rac Acetyl Ivabradine impurity Impurities CS-O-59338 Not Available Enquire
rac Ivabradine Impurity 27 Impurities CS-O-59373 Not Available Enquire
Rac-Ivabradine Hydrochloride Impurities CS-O-52418 1796933-38-4 Enquire
R-Ivabradine Impurities CS-O-54300 167072-91-5 Enquire
R-Ivabradine HCl Impurities CS-O-16957 148849-68-7 Enquire


Intermediates

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(3-bromopropyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepi... Intermediates CS-O-44651 1192174-72-3 Enquire
7-Demethyl Ivabradine Intermediates CS-T-52273 304462-60-0 Enquire
8-Demethyl Ivabradine Intermediates CS-T-16432 304464-97-9 Enquire
Dehydro Ivabradine Intermediates CS-T-51739 1086026-31-4 In Stock
Ivabradine Impurity 23 Intermediates CS-T-86358 85175-77-5 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(3-bromopropyl)-7,8-dimethoxy-1,3-dihydro-2H-3-benzazepin-... Fine Chemicals CS-O-34201 1428869-91-3 In Stock