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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Pregabalin, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Pregabalin impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Pregabalin-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Pregabalin Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-Pregabalin-13C3 (S)-Mandelic Acid Salt Stable Isotopes CS-T-102399 Not Available Enquire
4-Isobutyl-2-pyrrolidinone-13C3 (pregabalin lactam impurity) Stable Isotopes CS-T-101216 Not Available Enquire
Pregabalin-d4 Stable Isotopes CS-O-06883 1276197-54-6 In Stock
rac 4,5-Dehydro Pregabalin-13C3 Stable Isotopes CS-T-100555 Not Available Enquire
rac 5,6-Dehydro Pregabalin-13C3 Stable Isotopes CS-T-100554 Not Available Enquire
(S)-N-Methyl-d5 Pregabalin Stable Isotopes CS-T-80425 1246820-67-6 Enquire
(S)-Pregabalin-13C3 Stable Isotopes CS-T-94315 Not Available Enquire
Methylpregabalin-13C-D3 Stable Isotopes CS-CX-00543 313651-25-1 unlabeled Enquire
Pregabalin D6 Stable Isotopes CS-BX-00632 148553-50-8 (Unlabeled) Enquire
Rac-Pregabalin 13C3 Stable Isotopes CS-EK-02580 128013-69-4 unlabeled Enquire
rac-Pregabalin 13C3 Stable Isotopes CS-T-57141 1189980-48-0 Enquire
rac-Pregabalin-d4 Stable Isotopes CS-T-98709 Not Available Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Pregabalin API CS-O-08019 148553-50-8 In Stock
Pregabalin Mandelate API CS-EO-03786 1190093-99-2 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Methyl-pregabalin Metabolite CS-CX-00544 313651-25-1 Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(3S)-3-(2-Amino-2-oxoethyl)-5-methylhexanoic Acid Impurity CS-ED-00352 181289-34-9 In Stock
(E)-2-Hydroxy-3-isopropyl-6-methylhept-3-enenitrile Impurity CS-O-42704 Not Available Enquire
(E)-4-Methyl-2-pentenenitrile Impurity CS-O-42702 19124-15-3 Enquire
(E)-4-methylpent-2-enoic acid Impurity CS-O-43022 16666-43-6 Enquire
(E)-ethyl 4-methylpent-2-enoate Impurity CS-T-94637 15790-86-0 Enquire
(R)-3-(2-methoxy-2-oxoethyl)-5-methylhexanoic acid Impurity CS-O-56519 156048-92-9 Enquire
(R)-Pregabalin Impurity CS-O-05753 148553-51-9 In Stock
(S)-1-acetyl-4-isobutylpyrrolidin-2-one Impurity CS-EO-01365 1374336-43-2 In Stock
(S)-3-carbamoyl-5-methylhexanoic acid Impurity CS-O-42717 Not Available Enquire
(S)-3-cyano-5-methylhexanoic acid Impurity CS-T-94638 181289-37-2 Enquire
2-(2-ethoxy-2-oxoethyl)-4-methylpentanoic acid Impurity CS-O-42707 Not Available Enquire
2-(4-isobutyl-2-oxopyrrolidin-1-yl)acetic acid Impurity CS-O-37973 1511511-44-6 In Stock
2,6-dihydroxy-4-isobutylpyridine-3,5-dicarbonitrile Impurity CS-O-52654 861318-48-1 Enquire
2-Chloro Pregabalin impurity Impurity CS-O-48847 Not Available Enquire
2-Isopropyl-5-methyl-2-hexenal Impurity CS-O-42706 35158-25-9 Enquire
3-(bis(4-isobutyl-2-oxopyrrolidin-1-yl)methyl)-5-methylhexan... Impurity CS-O-51799 Not Available Enquire
3-Formyl-2-isobutyl-4-methylpentanenitrile Impurity CS-O-42703 Not Available Enquire
4,5-Dehydro Pregabalin Formate Impurity CS-O-58092 ---- Enquire
4,9-Diisobutyl-1,6-diazecane-2,7-dione Impurity CS-T-91780 1990538-03-8 Enquire
5,6-Dehydro Pregabalin Impurity CS-O-14985 1141362-94-8 Enquire
5-Chloro Pregabalin impurity Impurity CS-O-48846 Not Available Enquire
Diethyl 2-(3-Methylbutylidene)malonate Impurity CS-T-95950 51615-30-6 Enquire
ethyl 2-hydroxy-4-methylpentanoate Impurity CS-DE-01503 10348-47-7 Enquire
Isobutylglutarmonoamide (rac-Pregabalin amide impurity) Impurity CS-O-32267 181289-15-6 In Stock
Isovaleraldehyde cyanohydrin Impurity CS-T-94514 54129-53-2 Enquire
methyl 3-(2-amino-2-oxoethyl)-5-methylhexanoate Impurity CS-O-44586 1824451-15-1 Enquire
Mixture of Lactose Conjugates Impurity 2 & Pregabalin Impuri... Impurity CS-O-36618 466678-45-5 & 466678-46-6 In Stock
Potassium (S)-3-cyano-5-methylhexanoate Impurity CS-O-42708 Not Available Enquire
Pregabalin Amide Impurity CS-O-45151 1568181-40-7 Enquire
Pregabalin Amide dimer Impurity CS-O-42714 1083246-65-4 Enquire
Pregabalin Amide Ester Impurity Impurity CS-O-35643 ---- Enquire
Pregabalin Amine Amide Impurity Impurity CS-EO-02010 1567946-71-7 In Stock
Pregabalin Amine Amide Impurity (tartrate salt) Impurity CS-EO-03785 1567946-71-7 (Freebase) Enquire
Pregabalin Carbamoyl Impurity Impurity CS-T-10225 181289-33-8 In Stock
Pregabalin conjugate PD0224377 Impurity CS-O-03620 501665-97-0 In Stock
Pregabalin Conjugate PD0224377,PD0310886,PD0310887 (Mixture ... Impurity CS-O-56609 ---- Enquire
Pregabalin conjugate PD0224378 Impurity CS-T-84428 466678-44-4 In Stock
Pregabalin conjugate PD0224378 Impurity CS-O-03619 466678-44-4 In Stock
Pregabalin Conjugate PD0310806 Impurity CS-O-20055 ---- In Stock
Pregabalin Conjugate PD0310886 And PD0310887 (Mixture of iso... Impurity CS-O-20054 Not Available In Stock
Pregabalin DIESTER IMPURITY Impurity CS-O-42701 Not Available Enquire
Pregabalin DInitrile impurity Impurity CS-O-42705 Not Available Enquire
Pregabalin EP Impurity D Impurity CS-T-93316 4118-51-8 In Stock
Pregabalin Ethyl Ester Hydrochloride Impurity CS-O-44701 1909294-27-4 Enquire
Pregabalin Impurity 13 Impurity CS-EO-00661 466678-47-7 In Stock
Pregabalin Impurity 21 Impurity CS-O-37359 ---- Enquire
Pregabalin Impurity 36 Impurity CS-EO-02216 1094517-69-7 Enquire
Pregabalin Impurity 4 Impurity CS-O-14717 1477840-24-6 In Stock
Pregabalin Impurity 41 Impurity CS-EO-02780 ---- In Stock
Pregabalin Impurity 48 Impurity CS-O-48906 29882-69-7 Enquire
Pregabalin Impurity 7 Impurity CS-O-14720 1094517-98-2 Enquire
Pregabalin Impurity 8 Impurity CS-O-14721 181289-23-6 In Stock
Pregabalin Impurity B Impurity CS-O-13756 75143-89-4 In Stock
Pregabalin Impurity Mixture of PD0312236 & PD0312237 Impurity CS-O-20053 ---- In Stock
Pregabalin Lactam Impurity CS-M-45900 61312-87-6 In Stock
Pregabalin Lactose Aduct II Impurity CS-EO-01423 Not Available Enquire
Pregabalin Sec Amide Impurity CS-EO-00937 930585-94-7 Enquire
Pregabalin TRIESTER IMPURITY Impurity CS-O-42700 Not Available Enquire
Pregabalin Trimer impurity Impurity CS-O-35000 Not Available Enquire
PregabalinDIISOPROPYL IMPURITY Impurity CS-O-42699 Not Available Enquire
Rac 4,5-Dehydro Pregabalin Impurity CS-T-14978 216576-74-8 In Stock
rac 5,6-Dehydro Pregabalin Impurity CS-T-14980 1136478-30-2 Enquire
Rac-Pregabalin Amide dimer Impurity CS-T-103276 1486961-58-3 Enquire
rac-Pregabalin Methyl Ester Hydrochloride Impurity CS-O-48875 1955557-35-3 In Stock
R-Pregabalin Amide Lactose Adduct Impurity CS-EO-03215 501665-88-9 Enquire
tert-butyl 2-(4-isobutyl-2-oxopyrrolidin-1-yl)acetate Impurity CS-O-45814 Not Available Enquire
Urea impurity of pregabalin Impurity CS-O-42710 Not Available Enquire
(E) 2,3-Dehydro Pregabalin Impurity CS-P-08595 Not Available Enquire
(R)-4,5-Dehydro Pregabalin Impurity CS-O-14986 1101167-84-3 Enquire
(R)-5,6-dehydro Pregabalin Impurity CS-EO-00941 Not Available Enquire
(R)-Pregabalin EP Impurity D Impurity CS-O-14987 89015-27-0 Enquire
(S)​-​2-​Isobutylsuccinic acid Impurity CS-O-42716 63163-11-1 Enquire
(S)-1-benzyl-4-isobutylpyrrolidin-2-one Impurity CS-O-39917 1101167-78-5 Enquire
(S)-3-(isocyanato methyl)-5-methylhexanoic acid Impurity CS-O-36159 2102350-92-3 Enquire
(S)-4,5-Dehydro Pregabalin Impurity CS-T-74075 1141362-54-0 Enquire
(S)-4-isobutyldihydrofuran-2(3H)-one Impurity CS-O-39916 172796-26-8 Enquire
(S)-ethyl 3-cyano-5-methylhexanoate Impurity CS-O-40963 181289-39-4 Enquire
(S)-N-Methyl Pregabalin Impurity CS-T-81414 1155843-61-0 Enquire
(S)-Pregabalin Methyl Ester Impurity CS-T-40437 714230-22-5 Enquire
(Z)-2,3-Dehydro Pregabalin Impurity CS-O-36334 Not Available Enquire
3-(aminomethyl)-6-hydroperoxy-5-methylhexanoic acid Impurity CS-O-34975 Not Available Enquire
ethyl (1R,5S)-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylate Impurity CS-O-39915 184838-77-5 Enquire
Lactose Conjugates Impurity 2 Impurity CS-EO-00639 466678-45-5 Enquire
Pregabalin Cyano Impurity Impurity CS-T-51389 181289-16-7 Enquire
Pregabalin Diacid Impurity Impurity CS-T-29665 5702-99-8 Enquire
PREGABALIN DIISOBUTYL IMPURITY Impurity CS-O-42715 Not Available Enquire
Pregabalin dimer impurity Impurity CS-O-35397 2361911-35-3 Enquire
Pregabalin Impurity 1 Impurity CS-O-14714 ---- Enquire
Pregabalin Impurity 12 Impurity CS-EO-00660 466678-46-6 Enquire
Pregabalin Impurity 2 Impurity CS-O-14715 1928755-04-7 Enquire
Pregabalin Impurity 20 Impurity CS-O-39494 1464089-92-6 Enquire
Pregabalin Impurity 28 Impurity CS-P-08777 1026009-73-3 Enquire
Pregabalin Impurity 3 Impurity CS-O-14716 1928754-83-9 Enquire
Pregabalin Impurity 36 DiHCl Impurity CS-P-08593 159029-27-3 (free base) Enquire
Pregabalin Impurity 42 Impurity CS-O-39493 181289-21-4 Enquire
Pregabalin Impurity 5 Impurity CS-O-14718 Not Available Enquire
Pregabalin Impurity 6 Impurity CS-O-14719 Not Available Enquire
Pregabalin Impurity 9 Impurity CS-T-52703 185815-56-9 Enquire
Pregabalin Impurity E Impurity CS-EO-00783 1239692-16-0 Enquire
Pregabalin Impurity PD 0312236 Impurity CS-P-08888 Not Available Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-Carboxy Ethyl 3 Cyano-5 Methyl Hexanoicacid Ethyl Ester Intermediate CS-O-14923 186038-82-4 In Stock
2-Cyanoacetamide Intermediate CS-M-58432 107-91-5 In Stock
R(+)-1-phenylethylamine Intermediate CS-M-57238 3886-69-9 In Stock


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-(formamidomethyl)-5-methylhexanoic acid Fine Chemicals CS-O-37358 1488274-42-5 Enquire
4-Methylpentanal Fine Chemicals CS-T-34628 1119-16-0 Enquire


Building Blocks

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
(S)-N-Tert-Butoxycarbonyl Pregabalin Building Blocks CS-TA-83908 649748-09-4 Enquire