Flucinonide is a potent synthetic corticosteroid used to treat inflammatory skin conditions. During the manufacturing process, impurities may be introduced into the drug substance or product. These impurities can affect the quality, safety, and efficacy of the drug. Therefore, strict regulations and guidelines are in place to control and monitor the levels of impurities in Flucinonide. Identification and characterization of impurities are essential to ensure the purity of the drug substance or product.