Norgestimate is a progestin medication used as a contraceptive. However, during the manufacturing process, impurities may be introduced into the drug substance. These impurities can affect the quality, safety, and efficacy of the final product. Therefore, it is essential to monitor and control the levels of impurities in norgestimate to ensure that the medication meets the required regulatory standards. Some of the known impurities of norgestimate include desogestrel, ethynylestradiol, and norethindrone acetate.