Asciminib 13C6

Product Name Asciminib 13C6
CAT No. CS-EK-02310
CAS No. 1492952-76-7 unlabeled
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Canonical Smiles C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=CC=NN4
InchIKey VOVZXURTCKPRDQ-CQSZACIVSA-N
Inchl InChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1
IUPAC N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide
Controlled No
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[13C6]-Asciminib is a labeled form of the drug Asciminib, also known as ABL001. Asciminib is a novel drug that is currently being developed for the treatment of chronic myeloid leukemia (CML), a type of cancer that affects the blood and bone marrow. The drug works by inhibiting the activity of the BCR-ABL protein, which is responsible for the growth and division of cancer cells. [13C6]-Asciminib is a stable isotope-labeled form of Asciminib that is used in pharmacokinetic studies. It is used to track the metabolism and distribution of Asciminib within the body, allowing researchers to better understand how the drug is processed and eliminated. The chemical formula of [13C6]-Asciminib is C29H33ClN6O4S2, and it has a molecular weight of 630.22 g/mol. The labeled carbon atoms in [13C6]-Asciminib are located in the pyridine ring and the benzene ring of the molecule. The dosage and administration of [13C6]-Asciminib will depend on the specific study protocol being used. However, it is typically administered orally and is measured using liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques. Overall, [13C6]-Asciminib is a valuable tool for researchers studying the pharmacokinetics and metabolism of Asciminib. Its use allows for a better understanding of how the drug works in the body, which can ultimately lead to the development of more effective treatments for CML and other types of cancer.

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