Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-(methyl-13C-d3)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Sofosbuvir Metabolite GS-331007-13C,d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
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If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
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Sofosbuvir Metabolite GS-331007-13C,d3 usage and description
Sofosbuvir metabolite GS331007 13CD3 is a chemical compound used in the treatment of chronic hepatitis C virus (HCV) infection. It is a prodrug of the active antiviral agent Sofosbuvir, which is converted into GS331007 13CD3 in the body. The drug works by inhibiting the replication of the HCV RNA, which prevents the virus from infecting new liver cells. The use of Sofosbuvir metabolite GS331007 13CD3 has been shown to be highly effective in treating patients with HCV, both alone and in combination with other antiviral drugs.
Chemically, GS331007 13CD3 is a nucleoside analogue that is structurally similar to the natural nucleoside uridine. It is a prodrug, meaning that it is converted into the active form Sofosbuvir once it enters the body. GS331007 13CD3 is metabolized in the liver and converted into Sofosbuvir, which is then phosphorylated by cellular enzymes to form the active triphosphate form. The active triphosphate form of Sofosbuvir then acts as a chain terminator, preventing the HCV RNA polymerase from replicating the virus.
In conclusion, Sofosbuvir metabolite GS331007 13CD3 is a highly effective antiviral drug used in the treatment of chronic HCV infection. Its chemical structure and mechanism of action make it a valuable tool in the fight against HCV.
