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Clearsynth is a leading innovator in pharmaceutical reference standards, offering high-quality Reference Standards for Loratadine, including both pharmacopeial and non-pharmacopeial impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Our Loratadine impurity reference standards are invaluable for pharmaceutical research, supporting product development, ANDA and DMF submissions, quality control (QC), method validation, and stability studies. They also aid in identifying unknown impurities and assessing genotoxic potential.
Our Loratadine-related products undergo thorough characterization and are supplied with detailed Certificates of Analysis (COA) and analytical data that meet regulatory requirements. All supplied products are re-tested at regular intervals to ensure ongoing quality and compliance.

Loratadine Related Compounds

Stable Isotopes

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
3-Hydroxy Desloratadine-d4 Stable Isotopes CS-TB-66983 1246819-99-7 In Stock
5-Hydroxy Desloratadine-d4 Stable Isotopes CS-T-103265 117811-12-8 (Unlabelled) Enquire
6-Hydroxy Desloratadine-d4 Stable Isotopes CS-T-103266 119410-05-8 (Unlabelled) Enquire
Descarboethoxyloratadine-d6 diacetate Stable Isotopes CS-BU-00033 ---- Enquire
Desloratadine Citric Amide-d4 Stable Isotopes CS-T-96818 2714410-87-2 Enquire
Desloratadine-d4 Stable Isotopes CS-O-10056 381727-29-3 In Stock
Desloratadine-d4 (piperidinylidene-3,3,5,5-d4) Stable Isotopes CS-C-01294 2713301-38-1 Enquire
Desloratadine-d4 N-Carboxylic Acid Methyl Ester Stable Isotopes CS-T-100521 2732861-63-9 Enquire
Desloratadine-d5 Stable Isotopes CS-O-02713 1020719-34-9 Enquire
Desloratadine-d5 Hydrochloride Stable Isotopes CS-T-100520 Not Available Enquire
Loratadine-d4 Stable Isotopes CS-O-31235 381727-27-1 In Stock
Loratadine-d4 (piperidinylidene-3,3,5,5-d4) Stable Isotopes CS-C-00782 79794-75-5(Unlabelled) Enquire
Loratadine-d4 Epoxide N-Oxide Stable Isotopes CS-T-102892 1794754-14-5 Enquire
Loratadine-d5 (2,3,4,5,5-d5) Stable Isotopes CS-T-102349 1020719-57-6 In Stock
Loratadine-d5 (Ethyl-d5) Stable Isotopes CS-T-57296 1398065-63-8 In Stock
N-Formyl Desloratadine-d4 Stable Isotopes CS-T-100283 2733538-51-5 Enquire
N-Methyl Desloratadine-d5 Stable Isotopes CS-T-100025 Not Available Enquire
N-Nitroso Desloratadine-d4 Stable Isotopes CS-T-93987 2733579-31-0 In Stock
3-Hydroxy Desloratadine D4 Hydrobromide Stable Isotopes CS-O-02970 119410-08-1(Unlabeled)(Freebase) Enquire
3-Hydroxy Loratadine-D4 Stable Isotopes CS-T-78397 1189452-79-6 Enquire
3-Hydroxydescarboethoxy-Loratadine-D6 Stable Isotopes CS-BU-00097 Not Available Enquire
3-Methoxy Loratadine-d4 Stable Isotopes CS-T-57701 1189501-87-8 Enquire
3-Methoxy-N-methyldesloratadine D4 Stable Isotopes CS-T-57737 1189445-21-3 Enquire
5’-[(Desloratadine)methyl] Rupatadine-d8 Stable Isotopes CS-T-73540 1794669-33-2 Enquire
Desloratadine (2,2,6,6,10)-D5 Stable Isotopes CS-O-16050 1246819-67-9 Enquire
Desloratadine-d1 N-Oxide Stable Isotopes CS-T-74099 1794817-18-7 Enquire
Desloratadine-d7 (major) Stable Isotopes CS-T-73322 1795024-82-6 Enquire
Loratadine 13C6 Stable Isotopes CS-EK-00319 79794-75-5 unlabeled Enquire


API

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Desloratadine Hemisulfate API CS-ED-41814 731812-06-9 In Stock
Loratadine API CS-O-01778 79794-75-5 In Stock
Ethyl Isonipecotate API CS-T-75354 1126-09-6 Enquire


Metabolite

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
2-Hydroxymethyl Loratadine Metabolite CS-O-07891 609806-39-5 In Stock
4-Hydroxymethyl Loratadine Metabolite CS-O-06123 609806-40-8 In Stock
4-Hydroxymethyl Loratadine Hydrochloride Metabolite CS-T-93627 Not Available In Stock
Loratadine N-Oxide Metabolite CS-O-05927 165739-62-8 In Stock
3-Hydroxy Desloratadine Metabolite CS-O-05859 119410-08-1 Enquire
Desmethoxy loratadine Metabolite CS-O-05868 Not Available Enquire


Impurity

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
11-Hydroxy-N-methyl Dihydro Loratadine Impurity CS-T-55961 38089-93-9 In Stock
3-Hydroxy Loratadine Impurity CS-T-56118 183483-15-0 Enquire
5'-[(Desloratadine)methyl] Rupatadine Impurity CS-T-52178 1224515-72-3 In Stock
8-Deschloro-8-bromo Desloratadine Impurity CS-O-16658 117796-50-6 Enquire
Dehydro Loratadine Isomer A Impurity CS-EO-02258 2470226-18-5 Enquire
Deschloro Loratadine Impurity CS-T-88876 79779-58-1 In Stock
Deschlorodesloratadine Hydrochloride Impurity CS-O-32471 Not Available In Stock
Desloratadine 11-Hydroxy N-Methyl Impurity Impurity CS-EO-03475 38089-93-9 (Freebase) In Stock
Desloratadine 11-Hydroxy-N-Methyl Impurity(Mixture of isomer... Impurity CS-O-07773 38089-93-9 Enquire
Desloratadine Dehydro 11-Hydroxy N-Methyl Impurity Impurity CS-O-57149 117811-17-3 In Stock
Desloratadine Dehydro 11-Oxo Impurity Impurity CS-EO-00141 117811-16-2 In Stock
Desloratadine Dehydro N-Methyl Impurity Impurity CS-EO-03476 117811-18-4 (Freebase) Enquire
Desloratadine EP Impurity A Impurity CS-O-07778 298220-99-2 In Stock
Desloratadine EP Impurity B Impurity CS-O-07779 183198-49-4 In Stock
Desloratadine Methanone Hydrochloride Impurity Impurity CS-O-54167 119770-60-4 In Stock
Desloratadine N-Acetyl Impurity Impurity CS-O-07781 117796-52-8 In Stock
Desloratadine N-Carboxylic Acid Methyl Ester Impurity CS-T-52179 165740-03-4 In Stock
Desloratadine N-Formyl Impurity Impurity CS-O-07782 117810-61-4 In Stock
Desloratadine N-Oxide Impurity CS-T-52177 169253-26-3 In Stock
Desloratadine Related Compound B Impurity CS-O-49209 432543-89-0 Enquire
Iso Desloratadine Impurity CS-T-56802 183198-49-4 In Stock
Loratadine Cyano Impurity Impurity CS-O-32400 31255-57-9 In Stock
Loratadine EP Impurity A Impurity CS-CB-00047 133284-74-9 In Stock
Loratadine EP Impurity B Impurity CS-T-50635 31251-41-9 In Stock
Loratadine EP Impurity E Impurity CS-O-03616 170727-59-0 In Stock
Loratadine EP Impurity E HCl Salt Impurity CS-EO-03662 170727-59-0 (Freebase) Enquire
Loratadine EP Impurity F Impurity CS-O-14709 125743-80-8 In Stock
Loratadine EP Impurity G Impurity CS-O-07784 38092-89-6 In Stock
Loratadine Impurity 6 Impurity CS-P-08433 2183453-63-4 Enquire
Loratadine Impurity 9 Impurity CS-EO-02742 1449295-46-8 Enquire
Loratadine Impurity E Impurity CS-T-52591 133330-60-6 Enquire
11-Hydroxy Dihydro Desloratadine Impurity CS-T-78424 153200-97-6 Enquire
12-Fluoro Dihydroloratadine Impurity CS-P-08431 125743-79-5 Enquire
12-Hydroxy Loratadine Impurity CS-P-08432 Not Available Enquire
2-(2-oxopyrrolidin-1-yl)butanoic anhydride Impurity CS-O-36554 Not Available Enquire
2-Chloro Loratadine Impurity CS-T-72890 165739-64-0 Enquire
2-Formyl Loratadine Impurity CS-T-55044 1076198-15-6 Enquire
2-Methoxycarbonyl Loratadine Impurity CS-T-57646 860010-37-3 Enquire
3-Methoxy Desloratadine Impurity CS-T-57668 165739-63-9 Enquire
4-Chloro Loratadine Impurity CS-T-50704 165739-83-3 Enquire
4-Formyl Loratadine Impurity CS-T-55045 1076198-16-7 Enquire
8-Dechloro-10-chloro Desloratadine Impurity CS-T-73941 1346600-61-0 Enquire
8-Dechloro-10-chloro Loratadine Impurity CS-O-10168 1346605-16-0 Enquire
8-Dechloro-10-chloro-N-methyl Desloratadine Impurity CS-T-73184 38092-90-9 Enquire
8-Dechloro-7-chloro Desloratadine Impurity CS-T-73730 1346601-53-3 Enquire
8-Dechloro-7-chloro Loratadine Impurity CS-O-10169 1346602-19-4 Enquire
8-Dechloro-7-chloro-N-methyl Desloratadine Impurity CS-T-73250 1346600-30-3 Enquire
8-Dechloro-9-chloro Desloratadine Impurity CS-T-51687 117811-13-9 Enquire
8-Dechloro-9-chloro Loratadine Impurity CS-T-51688 109537-11-3 Enquire
8-Dechloro-9-chloro-N-methyl Desloratadine Impurity CS-T-51689 38092-88-5 Enquire
8-Deschloro-8-bromo Loratadine Impurity CS-T-88604 130642-60-3 Enquire
Dehydro Desloratadine Impurity CS-T-50913 117811-20-8 Enquire
Desloratadine 8-Bromo-11-Hydroxy-N-Methyl Impurity Impurity CS-O-07775 Not Available Enquire
Desloratadine 8-Bromo-11-Oxo Impurity Impurity CS-O-07776 143540-56-1 Enquire
Desloratadine Citric Amide Impurity CS-T-73339 1797131-43-1 Enquire
Desloratadine Epoxide Impurity CS-T-73103 1346604-23-6 Enquire
DESLORATADINE FOR SYSTEMSUITABILITY CRS (CONTANING IMPURITIE... Impurity CS-O-54438 ---- Enquire
Desloratadine N-Hydroxy Impurity Impurity CS-O-07783 1193725-73-3 Enquire
Ethyl 2-(2-oxopyrrolidin-1-yl) butanoyl carbonate Impurity CS-O-36553 Not Available Enquire
Loratadine Impurity 15 Impurity CS-O-37177 125743-81-9 Enquire
Loratadine LN8-bromo Impurity CS-O-39974 130642-51-2 Enquire
N-Methyl Iso Desloratadine Impurity CS-T-58300 183198-48-3 Enquire


Intermediate

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
5,6-Dehydro-N-methyl Desloratadine Intermediate CS-T-51737 117811-18-4 In Stock
8-Deschloro-8-bromo-N-methyl Desloratadine Intermediate CS-T-52065 130642-57-8 In Stock
Boc-Desloratadine Intermediate CS-Y-00096 1309283-27-9 In Stock


Glucuronide

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
6-Hydroxy Desloratadine β-D-Glucuronide Glucuronide CS-O-49082 956126-16-2 Enquire
Loratadine glucose adduct 1 Glucuronide CS-O-58221 ---- Enquire
Loratadine glucose adduct 2 Glucuronide CS-O-58222 ---- Enquire
3-Hydroxy Desloratadine-β-D-Glucuronide Glucuronide CS-T-55936 774538-89-5 Enquire


Fine Chemicals

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Iso Loratadine A Fine Chemicals CS-EO-00026 169253-13-8 Enquire


Nitrosamine

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Nitroso Desloratadine Nitrosamine CS-T-59617 1246819-22-6 In Stock


Secondary Standards

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Desloratadine Secondary Standards CS-SS-26628 100643-71-8 Enquire
Desloratadine Related Compound A Secondary Standards CS-SS-25194-50MG 117796-50-6 Enquire
Desloratadine Related Compound B Secondary Standards CS-SS-25195-50MG 432543-89-0 Enquire
Desloratadine Related Compound F Secondary Standards CS-SS-25196-100MG Not Available Enquire
Loratadine Secondary Standards CS-SS-24376-1GM 79794-75-5 Enquire
Loratadine Impurity A Secondary Standards CS-SS-25191-50MG 133284-74-9 Enquire
Loratadine Impurity E Secondary Standards CS-SS-25192-50MG 170727-59-0 Enquire
Loratadine Impurity H Secondary Standards CS-SS-25193-100MG 29976-53-2 Enquire
Loratadine Related Compound B Secondary Standards CS-SS-25189-50MG 38092-89-6 Enquire
Loratadine Related Compound C Secondary Standards CS-SS-25190-50MG 31251-41-9 Enquire


Analytical Standard

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
N-Nitroso Desloratadine Analytical Standard CS-T-59617-10MG 1246819-22-6 Enquire
N-nitroso-desloratadine-100 PPM in Acetonitrile Analytical Standard CS-T-59617-1.5ML 1246819-22-6 Enquire


Therapeutic

COMPOUND CATEGORY CAT. No. CAS. No. STOCK STATUS
Desloratadine Therapeutic CS-O-00556 100643-71-8 In Stock